Seoul Famotidine Tablets 20mg

Adult dosage

Oral administration: 1. For gastric ulcers, duodenal ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome: 20 mg once, twice a day (after breakfast, after dinner, or at bedtime) or 40 mg once a day (at bedtime). 2. For the improvement of gastric mucosal lesions in acute exacerbations of acute gastritis and chronic gastritis: 10 mg once, twice a day (after breakfast, after dinner, or at bedtime) or 20 mg once a day (at bedtime). Injection: Adults: Dissolve 20 mg of famotidine in 20 ml of normal saline or dextrose injection and slowly administer IV twice daily (every 12 hours) or mix with IV fluids and administer as an infusion. In cases of upper gastrointestinal bleeding and Zollinger-Ellison syndrome, effects generally appear within one week, and it is switched to oral administration once feasible. When used for preoperative sedation, dissolve 20 mg in 1-1.5 ml of injectable water and administer intramuscularly one hour before anesthesia or slowly inject it into 20 ml of normal saline or dextrose infusion one hour before anesthesia. After dissolution, it should be used within 48 hours if stored at room temperature or refrigerated. Adjust dosages according to age and symptoms.

This medication should not be used in patients who have had an allergic reaction to any ingredient or similar medications. Caution should be exercised when using this medication in patients with a history of allergies, impaired kidney function, heart disease, weakened liver function, and in elderly patients. This medication can cause severe side effects, so if symptoms such as shock, difficulty breathing, skin rash, blood abnormalities, arrhythmia, liver dysfunction, muscle pain, or changes in consciousness occur during use, the medication should be discontinued immediately and medical attention should be sought. During treatment, the patient's condition should be monitored frequently, and it should be used at the minimum effective dose; if ineffective, alternative treatments should be considered. This medication is taken orally by dissolving it in the mouth, but it should be swallowed with saliva or water to ensure it is not absorbed directly through the oral mucosa. Caution is advised in patients receiving hemodialysis who use this medication with specific phosphate binders, as the effectiveness of the phosphate binder may be diminished. This medication can interact with other drugs, particularly decreasing the effectiveness of antifungal agents or certain anticancer drugs, so all medications being taken should be disclosed to healthcare providers. Elderly patients may have reduced kidney function, allowing the medication to remain in the body longer; therefore, they should use a reduced dose or increased dosing interval with caution. Women who are pregnant or may become pregnant should only use this medication when the benefits outweigh the risks, and nursing mothers should consider discontinuing breastfeeding due to the potential transfer of the drug into breast milk. The safety of this medication in children has not been sufficiently established, so it is advisable to avoid its use in this population. In the case of orally disintegrating tablet formulations, the tablet should be placed on the tongue and dissolved with saliva before swallowing, and it should not be taken lying down without water. Finally, this medication may mask symptoms of stomach cancer, so it should only be used after confirming that it is not cancer.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), Stevens-Johnson syndrome, Lyell's syndrome (severe skin reactions), liver dysfunction, jaundice (liver abnormalities), altered consciousness, seizures (severe neurological symptoms), interstitial nephritis, acute renal failure, interstitial pneumonia (respiratory problems), contraction failure, QT prolongation, ventricular tachycardia, ventricular fibrillation, rhabdomyolysis, shock, hypersensitivity

Mild side effects

• Rash
• urticaria (redness)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• soft stools
• dry mouth
• nausea

This medication should be stored in a tightly closed container to prevent air ingress and should be kept at room temperature away from direct sunlight. Proper storage conditions will help maintain the medication's effectiveness for a longer period.

Appearance

White round film-coated tablet

Package unit

500 tablets/bottle, 30 tablets/bottle