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Prescription medication

Bukwang Ketoprofen Injection 100 mg

Relief of pain from rheumatoid arthritis and osteoarthritis (degenerative joint disease)

Bu-Kwang Pharmaceutical Co., Ltd.

Key information summary

Efficacy & effects
Relief of pain from rheumatoid arthritis and osteoarthritis (degenerative joint disease)
Adult dosage
(Capsule) For ketoprofen, administer 50 to 100 mg orally twice daily. Adjust as necessary based on symptoms. (Injection) For ketoprofen, administer 100 mg intramuscularly once to twice daily, in cases of severe conditions administer 100 mg twice daily. Long-term administration should be avoided and switch to oral form when the condition improves. Adjust as necessary based on symptoms.
Ingredients
Ketoprofen
Rx / OTC
Prescription medication
Appearance
Brown glass ampoule injection

Efficacy & effects

This medication is available in capsule and injection forms, primarily used for the treatment of rheumatoid arthritis, osteoarthritis (degenerative joint disease), as well as inflammation and pain occurring after trauma or surgery. The injection form is particularly effective for treating ankylosing spondylitis and acute gout. This medication helps improve the patient's daily life by reducing inflammation and alleviating pain. Therefore, it is widely used for rheumatoid arthritis, joint-related diseases, and acute pain management.

Dosage

(Capsule) For ketoprofen, administer 50 to 100 mg orally twice daily. Adjust as necessary based on symptoms. (Injection) For ketoprofen, administer 100 mg intramuscularly once to twice daily, in cases of severe conditions administer 100 mg twice daily. Long-term administration should be avoided and switch to oral form when the condition improves. Adjust as necessary based on symptoms.

Precautions

Individuals who regularly consume more than three alcoholic beverages daily should consult with a physician or pharmacist before taking this medication. Otherwise, there may be a risk of liver damage or gastrointestinal bleeding. This medication can pose a risk to the cardiovascular system, potentially leading to serious issues like heart attack or stroke; thus, those with cardiovascular disease or risk factors should exercise extra caution. If cardiovascular symptoms develop, medical attention should be sought immediately. It may also have gastrointestinal effects, with a risk of serious problems such as bleeding, ulceration, or perforation in the stomach or intestines, particularly heightened in older individuals. If symptoms of gastrointestinal bleeding or ulceration occur during treatment, immediate medical attention is required. Care should be taken when using this medication with other drugs. For example, co-administration with oral corticosteroids, anticoagulants, selective serotonin reuptake inhibitors, or antiplatelet medications may exacerbate side effects by increasing bleeding risk. When using injections, caution should be exercised to avoid breaking glass ampoules, ensuring no glass fragments are introduced. Special care is required, particularly when administered to children or the elderly. This medication should not be administered to individuals with a history of peptic ulcers, bleeding, or perforation, as well as those with severe liver, kidney, or heart disease, or to those who have allergies to aspirin or other non-steroidal anti-inflammatory drugs or have asthma. Patients with blood disorders or liver, kidney, or heart diseases should use this medication cautiously and require regular check-ups to monitor for symptom exacerbation. During treatment, if any abnormal symptoms such as allergic reactions, gastrointestinal bleeding, liver or kidney dysfunction, skin rash, headache, dizziness, visual or auditory disturbances occur, the medication should be discontinued immediately and a healthcare professional consulted. It is advisable to avoid use during the early and mid-stages of pregnancy, and particularly in the late stages, as it may have serious effects on the fetus; it should not be administered under any circumstances. Women who are breastfeeding should also refrain from taking this medication as it may affect the baby, and discontinuation of breastfeeding or the medication is recommended. Safety for pediatric use has not been established, so it is best not to administer this medication to children. Elderly patients may experience more severe side effects; a lower dose should be initiated with the shortest duration possible, and their condition should be closely monitored. Caution should be exercised while taking this medication as drowsiness or dizziness may occur, affecting the ability to drive or operate machinery. In cases of overdose, as there is no specific antidote, treatment may include gastric lavage, hydration, symptomatic treatment, and in cases of renal failure, dialysis may be helpful. This medication should only be administered via intramuscular injection, and mixing it with other medications for injection should be avoided.

Side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions Severe rashes, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions Asthmatic attacks, respiratory abnormalities accompanied by coughing and fever Jaundice of the skin or eyes, extreme fatigue, symptoms of liver dysfunction (jaundice) Sudden and severe headache, seizures, confusion, visual disturbances, paralysis, etc.

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