Colchicine Tablets (Colchicine)

Adult dose

1. Treatment of gout attacks At the first sign of a gout attack in adults, take 1.2mg of colchicine, followed 1 hour later by 0.6mg. Higher doses have not shown greater efficacy, and the maximum recommended dose is 1.8mg over 1 hour. If the first sign of a gout attack occurs while taking this medicine for prevention, take a dose not exceeding 1.2mg, followed by an additional 0.6mg 1 hour later. Resume the preventive dose after 12 hours. 2. Prevention of gout attacks Adults: Take 0.6mg 1~2 times daily. The maximum recommended dose is 1.2mg per day.

This medication should not be used by individuals with specific allergic reactions. Pregnant women or those who may become pregnant, as well as breastfeeding individuals, should not take this medication. Patients with severe gastrointestinal disorders or liver, kidney, heart, or blood-related conditions should also not use this medication. Patients with impaired liver or kidney function who are taking certain medications concurrently should use caution. This medication contains lactose; individuals with lactose intolerance or related genetic disorders should not take it. Elderly or frail patients, especially those with kidney, gastrointestinal, or heart issues, should use this medication cautiously. Patients allergic to the dye components contained in this medication should also exercise caution. Long-term use may lead to issues such as reduced blood cell counts or decreased bone marrow function, necessitating regular monitoring. If abnormal muscle symptoms such as muscle pain, weakness, or increased levels of certain enzymes in the blood appear, use should be immediately discontinued. Peripheral nerves may be affected, so careful observation is required if symptoms like numbness or sensory abnormalities occur. If symptoms like hair loss, skin rash, or hematuria develop, use should be promptly stopped. Gastrointestinal symptoms may include diarrhea, nausea, vomiting, or abdominal pain, and in such cases, the dosage may be reduced or temporarily halted. If allergic reactions such as itching, rash, or fever occur, use must be discontinued, and medical attention should be sought. There have been reports of weakness or temporary reproductive dysfunction. In case of overdose, severe symptoms such as nausea, vomiting, abdominal pain, diarrhea, hematuria, central nervous system abnormalities may arise, so it is crucial to adhere to the prescribed dosage and administration. Long-term use requires regular tests for blood, liver, and kidney functions, and during treatment, it is advisable to avoid grapefruit or grapefruit juice consumption. If muscle weakness, increased bleeding, heightened infection risk, or severe gastrointestinal symptoms occur, immediate medical contact is necessary. The risk of side effects may increase when using this medication alongside certain immunosuppressants, antibiotics, or lipid-lowering agents, so it is essential to consult healthcare providers beforehand. Pregnant or breastfeeding women should not take this medication due to potential risks to the fetus or newborn, and safety in pediatric populations has not been established. Elderly individuals may maintain higher blood levels of the drug, thus requiring dosage adjustment and monitoring of their condition. In cases of overdose, emergency treatments including gastric lavage, drug absorption, or intravenous therapy may be needed, and this drug cannot be removed by dialysis. This medication may affect urine test results, so it is important to inform healthcare providers during examinations. Store this medication out of reach of children, kept sealed in its original container.

• Bone marrow suppression
• agranulocytosis
• leukopenia
• aplastic anemia
• thrombocytopenia
• rhabdomyolysis
• myopathy
• myalgia
• weakness
• elevated CPK

This medication should be stored in a sealed container that blocks light, at a temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug's efficacy and prevents degradation.

Appearance

Pale yellow round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle