Medication info
Zanapam Tablet 0.5 mg (Alprazolam)

Zanapam Tablet 0.5 mg (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.5mg / 1 tablet
Manufacturer / importer
Myung In Pharmaceutical Co., Ltd.
Appearance
Orange oval tablet
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 198702210 · Approved 1987.12.02 · Insurance code 651901750

Summary

Main use
Relief of symptoms of anxiety (including anxiety disorders and anxiety accompanying depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
To achieve the greatest benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible period and frequently reassess the need to continue treatment. ○ Adults 1. As the initial dose, administer 0.25-0.5㎎ of alprazolam per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, increase it gradually up to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average total daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a slower reduction may be necessary in some cases.

Ingredients

Manufacturer
Myung In Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety (including anxiety disorders and anxiety accompanying depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety accompanying depression
  • anxiety
  • tension
  • depression
  • sleep disorders in psychosomatic disorders
  • panic disorder
View approved original text

This medication is used to treat mental health issues such as anxiety disorders and panic disorders. It also alleviates anxiety symptoms accompanying depression and improves anxiety, tension, depression, and sleep disorders occurring in psychosomatic disorders such as gastric or duodenal ulcers and irritable bowel syndrome. It is used to effectively relieve symptoms of various anxiety-related conditions.

How to take

Adult dose

To achieve the greatest benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible period and frequently reassess the need to continue treatment. ○ Adults 1. As the initial dose, administer 0.25-0.5㎎ of alprazolam per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, increase it gradually up to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average total daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a slower reduction may be necessary in some cases.

Precautions

This medication acts on the central nervous system and is a benzodiazepine used for alleviating anxiety and treating panic disorders. Taking this medication with other narcotics can lead to severe sedation, respiratory depression, coma, or death, so it should only be used at the minimum effective dose and for the shortest duration necessary. There is a risk of abuse and dependency while using this medication, so careful observation should be maintained according to the physician's instructions during use. This medication should not be used in patients with certain conditions such as hypersensitivity to the drug, acute closed-angle glaucoma, severe myasthenia gravis, severe respiratory failure, or severe liver failure. Also, pregnant women in late pregnancy, patients with alcohol or drug dependence, and patients with certain enzyme deficiencies should not take this medication. Patients with heart, liver, or kidney problems, elderly patients, or frail individuals may experience exacerbated side effects from this medication, so it should be used with caution. Drowsiness, decreased attention, etc., may occur during use, so it is best to avoid driving or operating dangerous machinery. For long-term use, regular blood tests and liver function tests are recommended. Abruptly stopping this medication may cause withdrawal symptoms such as anxiety, insomnia, tremors, and seizures, so it should be tapered off gradually under a doctor’s supervision. This medication can enhance effects and increase the risk of side effects when taken with other central nervous system depressants, alcohol, certain antifungals, antidepressants, etc. Therefore, caution is advised. If pregnant or breastfeeding, consult a doctor before use, as it can affect the fetus and newborn. Safety has not been established in children under 18 years of age, and elderly patients are at higher risk of side effects, so starting with a lower dose is advisable. In case of overdose, severe drowsiness, coma, respiratory depression, etc., may occur, and appropriate treatment should be sought immediately at a hospital. This medication should be stored out of reach of children and in its original container to prevent misuse.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • trembling
  • spasms
  • seizures
  • agitation
  • increased muscle rigidity
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  • sleep disturbances
  • hallucinations
  • anxiety
  • rage
  • irritability
  • aggressive behavior
  • hostile behavior
  • hyperirritability
  • animosity
  • obsessive thoughts
  • drowsiness
  • headache
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • neuroticism
  • increased libido
  • mania
  • hypomania
  • drug dependence
  • aggression
  • abnormal thinking
  • process dyskinesia
  • drug abuse
  • memory impairment
  • dysarthria
  • dizziness
  • balance disorders
  • coordination disorders
  • attention deficit disorder
  • hypersomnia
  • narcolepsy
  • amnesia
  • autonomic nervous system imbalance
  • abnormal muscle tone
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • hepatitis
  • impaired liver function
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reaction
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • irregular menstruation
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • delirium
  • insomnia
  • neuroticism
  • syncope
  • lightheadedness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • ankylosis
  • trembling
  • dermatitis
  • nasal congestion
  • weight gain
  • weight loss
  • drowsiness
  • fatigue
  • motor coordination disorders
  • hypersensitivity
  • memory impairment
  • headache
  • cognitive impairment
  • anxiety
  • involuntary movement disorders
  • decreased libido
  • delirious state
  • muscle single contraction
  • increased libido
  • changes in libido
  • weakness
  • abnormal muscle tone
  • syncope
  • inability to sit still
  • anxiety
  • disinhibition
  • sensory abnormalities
  • polyuria
  • vascular dysregulation
  • derealization
  • abnormal dreams
  • terror
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory tract infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urinary disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • seizures
  • depersonalization
  • taste changes
  • diplopia
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • lethargy
  • falls
  • ataxia
  • excessive sedation
  • incoherent speech
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a light-protective container. Also, to maintain effectiveness, it is important to store it at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

Orange oval tablet

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.