Alprazolam 0.25 mg Tablet (Alprazolam)

Adult dose

To achieve the greatest benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible period and frequently reassess the need to continue treatment. 1. As the initial dose, administer 0.25-0.5㎎ of alprazolam per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, increase it gradually up to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average total daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a slower reduction may be necessary in some cases.

This medication is a benzodiazepine drug that acts on the central nervous system to produce sedative and anxiety-relieving effects. However, taking it in combination with narcotics can excessively enhance sedative effects, leading to the risk of respiratory depression or coma. Therefore, it should not be taken together unless absolutely necessary. This drug has a risk of misuse and dependence; thus, it should only be taken according to a doctor's instructions for the exact dosage and duration, and any remaining medication should be stored or disposed of safely. Patients with allergies to alprazolam or any ingredients in this medication, acute closed-angle glaucoma, severe liver or kidney dysfunction should not take this medication. It should not be administered in late pregnancy as it could affect the fetus, and breastfeeding mothers should avoid taking it as it can be transferred into breast milk and affect the baby, so they should either avoid taking it or stop breastfeeding. Elderly or frail patients should begin with a low dose due to possible side effects of clumsiness or excessive sedation. This medication requires caution while driving or operating dangerous machinery due to drowsiness and decreased concentration. For long-term use, it is recommended to undergo regular liver function and blood tests. Suddenly stopping the medication can result in withdrawal symptoms including anxiety, insomnia, tremors, seizures, hence the dosage should be gradually reduced under a doctor's guidance. Combining this medication with alcohol or other central nervous system depressants can exacerbate side effects, thus co-administration should be avoided. In case of overdose, severe drowsiness, coma, respiratory depression may occur, necessitating immediate hospital treatment. Keep out of reach of children and store in the original container to prevent misuse.

• Mild discomfort
• insomnia
• abdominal and muscle cramps
• vomiting
• sweating
• trembling
• convulsions
• seizures
• agitation
• increased muscle rigidity

This medication should be stored in a tight, light-protected container at room temperature, avoiding extreme temperatures (too hot or too cold). Proper storage will help maintain the medication's effectiveness and prevent it from degrading.

Appearance

White oval-shaped tablet

Package unit

30 tablets/bottle, 200 tablets/bottle, 200 tablets (10 tablets/PTP × 20)