Medication info

Comadin Tablets 100 Milligrams (Clotrimazole)

OTC medicationVaginal tabletApproval withdrawn
Ingredient · strength
Clotrimazole›100mg / 1 tablet
Manufacturer / importer
지엘파마(주)
Appearance
It is a white, oblong vaginal tablet.
Packaging
6 tablets/foil
Approval status
Approval withdrawn

MFDS item code 198701674 · Notified 1987.05.01

This product's status changed to Approval withdrawn on 2023.12.21. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of candidal vaginitis
Who uses it
Adults
Adult dosage
Adults: Normally, insert 100 mg of clotrimazole deep into the vagina once daily for 6 consecutive days at bedtime. For a short-term regimen, normally insert 200 mg of clotrimazole deep into the vagina once daily for 3 consecutive days at bedtime.

Ingredients

Manufacturer
지엘파마(주)

Efficacy & effects

Treatment of candidal vaginitis

  • Candidal vaginitis
View approved original text

Candidal vaginitis is an inflammatory disease that occurs due to excessive proliferation of Candida in the vagina. This medication is used to treat candidal vaginitis.

Dosage and Administration

Adult dosage

Adults: Normally, insert 100 mg of clotrimazole deep into the vagina once daily for 6 consecutive days at bedtime. For a short-term regimen, normally insert 200 mg of clotrimazole deep into the vagina once daily for 3 consecutive days at bedtime.

Precautions

This medication should not be used by individuals who have had allergic reactions to the active ingredient or its components. This medication contains lactose, so individuals with a genetic disorder that prevents lactose digestion should not take it. During the use of this medication, it should not be used together with certain immunosuppressants such as tacrolimus or sirolimus; if it must be used together, drug levels in the blood should be carefully monitored. Women who are pregnant or may become pregnant should consult a healthcare professional before using this medication. Caution should be taken during early pregnancy when using this medication, and it is advisable to avoid the use of intravaginal devices during pregnancy. Women who are breastfeeding are recommended to discontinue breastfeeding during the duration of use, as this medication may be excreted in breast milk. If any allergic reactions or abnormal symptoms such as rashes, itching, pain, or bleeding occur while using this medication, usage should be immediately stopped and a healthcare professional consulted. It is advisable not to use this medication during menstrual periods, and to avoid using vaginal cleansers or tampons during treatment. Intercourse should be avoided during the treatment period, and partners may also need treatment to prevent infection. Care should be taken to avoid contact with the eyes, and it must not be swallowed. If symptoms like high fever, lower abdominal pain, or foul-smelling vaginal discharge occur, consult a doctor immediately. There is no specific antidote in case of overdose; however, if a large amount is accidentally swallowed, emergency measures such as gastric lavage should be taken as soon as possible. This medication may weaken condoms or intravaginal contraceptive devices, so they should be avoided together. This medication is for vaginal use only and should not be taken orally. It is recommended for use by children over 12 years old and adults only. When storing, keep out of the reach of children and seal it in its original container, keeping it in a cool, dry place away from direct sunlight.

Side effects and when to seek care immediately

Serious side effects

  • Fainting
  • low blood pressure
  • difficulty breathing
  • hives
  • allergic reactions of the immune system
  • peeling skin in the genital area
  • high fever (over 38˚C)

Mild side effects

  • Abdominal pain
  • lower abdominal cramps
  • itching
  • rash
  • swelling (edema)
  • erythema (red spots)
  • discomfort
  • burning sensation
  • irritation
  • pelvic pain
Show 6 more
  • vaginal bleeding
  • mild frequent urination
  • nausea
  • foul-smelling vaginal discharge
  • lower back pain
  • shoulder pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. It should also be placed in a well-sealed container to avoid air exposure, and should be stored at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

It is a white, oblong vaginal tablet.

Package unit

6 tablets/foil

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.