Medication info

Messiran Injection (Pridinol Mesylate)

Prescription medicationSolutionIntravenous injectionExpired
Ingredient · strength
Pridinol Mesylate›2mg / 1 ampoule
Manufacturer / importer
Hanol Bio Pharma Co., Ltd.
Appearance
A brown ampoule containing a colorless, transparent solution.
Packaging
1mL/ampoule x 50 ampoules
Approval status
Expired

MFDS item code 198700321 · Notified 1987.04.20

This product's status changed to Expired on 2025.10.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of painful muscle spasms associated with musculoskeletal disorders (e.g., lumbago and cervicobrachial syndrome)
Who receives it
Adults
Adult administration
Adults: Administer 2㎎ of pridinol mesylate once daily by intramuscular or intravenous injection. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Hanol Bio Pharma Co., Ltd.

Efficacy & effects

Relief of painful muscle spasms associated with musculoskeletal disorders (e.g., lumbago and cervicobrachial syndrome)

  • Painful spasms associated with musculoskeletal disorders
  • low back pain
  • shoulder-arm syndrome
  • periartritis of the shoulder
  • degenerative spondylosis
View approved original text

This medication is used to relieve pain and muscle stiffness associated with musculoskeletal disorders. Specifically, it is effective for low back pain, cervical-shoulder pain, and periartritis of the shoulder. It also helps with discomfort caused by degenerative spondylosis. This drug relaxes muscles and reduces pain, thereby improving discomfort in daily life. It is therefore used effectively for pain and spasms related to the musculoskeletal system.

How it is given

Adult administration

Adults: Administer 2㎎ of pridinol mesylate once daily by intramuscular or intravenous injection. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication may have glass fragments due to the use of ampoule injections, so caution is required when cutting the container. Special care is needed when used in children and the elderly. This drug should not be administered to certain patients. For instance, patients with hypersensitivity to this medication or those with glaucoma should not use it as it may increase intraocular pressure. Patients with urinary difficulties due to prostatic hyperplasia may experience worsening symptoms due to the anticholinergic effects of this medication, so it should also be avoided. Patients with severe heart diseases, paralytic ileus, megacolon, acute pulmonary edema, tachycardia, severe arteriosclerosis, and gastrointestinal obstruction should avoid using this drug as it may worsen their symptoms. Patients with liver or kidney dysfunction should use this drug cautiously. Side effects may include hypersensitivity reactions such as rash and urticaria, and in rare cases, symptoms similar to anaphylaxis or shock may occur. It may affect the nervous system, leading to dizziness, drowsiness, anxiety, and hallucinations, and if such symptoms appear, the dosage should be reduced or administration should be stopped. Muscle relaxation or weakness may rarely occur, and gastrointestinal symptoms such as dry mouth, nausea, and vomiting may also be present. Skin rashes or erythema, visual accommodation disorders, and worsening of glaucoma should also be monitored. When taking this medication, drowsiness or decreased attention may occur, so driving or operating hazardous machinery should be avoided. When taken with other central nervous system depressants or specific medications, interactions may enhance the effects, so caution is necessary during co-administration. Women who are pregnant or may become pregnant should only use this medication if its benefits outweigh the risks, and during breastfeeding, it is advisable to avoid administration as the drug may be transmitted through breast milk. In children or the elderly, dosage adjustment and careful administration are needed as safety is not fully confirmed or bodily functions may be impaired. This drug should only be used as an injection when oral administration is not possible, and when injected, it is safer to dilute it with saline or glucose solution and administer it slowly. The intravenous injection should be performed with the patient lying on their side.

Side effects

  • Rash
  • hives
  • anaphylactic symptoms
  • shock-like symptoms
  • dizziness
  • unsteadiness
  • fainting
  • drowsiness
  • anxiety
  • hallucinations
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  • weakness
  • lethargy
  • muscle relaxation
  • myasthenia
  • inability to sit for long periods
  • thirst
  • nausea
  • vomiting
  • decreased salivation
  • erythema
  • difficulties in visual accommodation
  • angle-closure glaucoma

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is important to maintain a cool room temperature, between 1 degree and 30 degrees Celsius, when storing the drug. This helps to maintain the drug's efficacy for a long time.

Appearance and packaging

Appearance

A brown ampoule containing a colorless, transparent solution.

Package unit

1mL/ampoule x 50 ampoules

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.