
Key information summary
Efficacy & effects
This medication is effective for rheumatoid arthritis, osteoarthritis, fever and pain due to colds, low back pain, dysmenorrhea, and postoperative pain when taken orally. It is also used for various pains and inflammation such as ankylosing spondylitis, headache, toothache, muscle pain, neuralgia, acute gout, psoriatic arthritis, and soft tissue damage. The suppository form is primarily used for fever due to acute upper respiratory tract infection in children. This medication helps alleviate various inflammatory diseases and pain, improving the quality of life for patients.
Dosage
For rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue damage, non-articular rheumatic diseases, acute gout, and psoriatic arthritis, administer 200-600 mg orally 3-4 times a day, with a maximum daily dose of 3200 mg. For mild to moderate pain and cold symptoms, administer 200-400 mg orally 3-4 times a day, adjusting according to age and symptoms.
Precautions
People who regularly consume more than three glasses of alcohol daily should consult a healthcare professional before taking this medication. This is because taking this medication may increase the risk of gastrointestinal bleeding. Individuals with cardiovascular diseases or risk factors may experience an increased likelihood of cardiovascular issues such as myocardial infarction and stroke when taking this medication. Particularly caution is advised when taking high dosages or over extended periods. Severe gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforation can also occur while taking this medication, so elderly patients and those on long-term medication should be especially careful. Patients with a history of gastrointestinal ulcers or bleeding, severe blood disorders, liver dysfunction, kidney impairment, heart failure, or severe hypertension should not take this medication. Those with hypersensitivity to this medication or who have had allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should also avoid taking it. Pregnant women in the late stage should avoid using this medication as it may harm the fetus. When taking this medication, the recommended dosage should not be exceeded, and it is advisable not to take it in conjunction with other non-steroidal anti-inflammatory drugs. If breast-feeding, this medication can pass into breast milk and cause adverse reactions in the baby, so it is necessary to either discontinue breastfeeding or stop taking the medication. Patients with a history of blood disorders, liver or kidney disease, heart disease, hypertension, or hypersensitivity should consult a healthcare professional before taking this medication. This medication can interact with various other medications; therefore, inform your doctor or pharmacist about any other medications you are currently taking. If you experience sudden allergic reactions, severe skin rashes, difficulty breathing, symptoms of gastrointestinal bleeding, liver dysfunction, or kidney function decline while taking this medication, you should stop taking it immediately and consult a medical professional. It is safest to take this medication for the shortest duration possible at the minimum effective dose, and regular check-ups are needed for long-term use. Keep this medication out of reach of children, and store it in its original container to prevent misuse or deterioration of quality.
Side effects
Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rashes with high fever, vesicular dermatitis (blisters), skin shedding, pain in mucous membranes of the mouth/eyes, severe adverse skin reactions, asthma attacks, respiratory issues accompanied by cough and fever, shortness of breath or difficulty breathing, respiratory problems, yellowing of the skin or eyes (jaundice), profound lethargy, liver dysfunction
Interactions
Do not take this medication in combination with high-dose methotrexate during chemotherapy. Patients taking low-dose aspirin, ACE inhibitors, lithium, furosemide, thiazide diuretics, low-dose methotrexate, coumarin anticoagulants, and selective serotonin reuptake inhibitors should consult their doctor or pharmacist.

