Hepamelz Infusion Injection (L-Aspartic Acid-L-Ornithine)

Adult administration

For hepatic encephalopathy, L-Aspartic Acid-L-Ornithine is mixed with an appropriate intravenous fluid for slow intravenous infusion up to 40 g (8 ampules) per day. Adjust as necessary according to symptoms.

This medication comes in a glass ampule injection form, and care should be taken when cutting to prevent glass particles from entering. Extra caution is required when used in children or the elderly. This medication should not be administered to certain patients. It can be dangerous for patients with lactic acidosis, methanol poisoning, fructose-sorbitol intolerance, fructose-1,6-diphosphatase deficiency, and severe renal failure. Additionally, this medication contains sodium pyrosulfite, which can cause allergic reactions or asthma attacks in individuals allergic to sulfites, so it should be used with caution. When using this medication, side effects such as a hot feeling in the back of the head, nausea, gastrointestinal discomfort, and vomiting may occasionally occur. In the case of high-dose administration, blood or urine urea levels should be monitored, and infusion rates should be adjusted to reduce discomfort or vomiting in patients with poor liver function. This medication should be administered slowly by intravenous injection, as rapid administration can be dangerous. When storing, it should be kept in a safe place out of reach of children, and sealed in its original container. Transferring it to another container increases the risk of misuse or degradation of quality.

Serious side effects

Allergic reactions such as sulfite anaphylaxis, asthma attacks

Mild side effects

• Tingling warmth at the back of the head
• nausea
• gastrointestinal discomfort
• vomiting

This medication should be stored in a sealed container and kept at a safe temperature between 1 degree Celsius and 30 degrees Celsius. Storing it this way will maintain the effectiveness of the medication and prevent degradation.

Appearance

A transparent liquid that is colorless to pale yellow filled in a brown ampule.

Package unit

10 ampules/box [(10 milliliters/ampule)]