Herbenc Extended-Release Tablets 90 mg (Diltiazem Hydrochloride)

Adult dosage

(Oral: extended-release capsules) 1. Adults: Administer diltiazem hydrochloride 180㎎ orally once daily. The dose may be increased to 360㎎ per dose according to symptoms. 2. Older adults and patients with hepatic or renal impairment: Administer 90-120㎎ once daily as the initial dose. Measure the heart rate during treatment; do not increase the dose if it falls to 50 beats or fewer. Adjust the dose according to age and symptoms. (Oral: extended-release tablets 30㎎) Adults: Administer diltiazem hydrochloride 30-60㎎ per dose orally 3 times daily. Adjust the dose according to age and symptoms. (Oral: extended-release tablets 90㎎) Adults: Administer diltiazem hydrochloride 90㎎ per dose orally 2 times daily. If necessary, the dose may be increased to 90-180㎎ per dose. Adjust the dose according to age and symptoms. (Injection) Dissolve this drug in at least 5㎖ of saline or dextrose injection and administer as follows. 1. Tachyarrhythmia (supraventricular) Adults: Slowly inject diltiazem hydrochloride 10㎎ intravenously over approximately 3 minutes. 2. Emergency treatment of abnormal hypertension during surgery ① Intravenous bolus injection Adults: Slowly inject 10㎎ intravenously over approximately 1 minute. ② Intravenous infusion Adults: Infuse 5-15㎍ per kg of body weight intravenously over 1 minute. After reducing blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. 3. Hypertensive emergency (hypertensive crisis) Adults: Infuse 5-15㎍ per kg of body weight intravenously over 1 minute. After reducing blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. Adjust the dose according to age and symptoms.

This medication should not be used in patients with heart function issues or severely low blood pressure. It is also safer for women who are pregnant or may become pregnant to avoid taking this medication. Patients with severely impaired liver or kidney function need to be cautious as the drug may not be properly metabolized and excreted, leading to an increased risk of side effects. Patients with abnormal heart rhythms or certain cardiac conduction disorders should also be careful when using this medication. This medication can cause multiple side effects, with common occurrences including headaches, nasal congestion, cough, constipation, and muscle pain. Cardiac-related side effects may include bradycardia, arrhythmia, and lowered blood pressure; if unusual symptoms occur, consult a doctor immediately. Skin rashes or itching may occur, and in severe cases, peeling of the skin may happen; if these symptoms arise, discontinue medication and visit a hospital. Discontinuing this medication abruptly can worsen symptoms, so dosage should be gradually reduced following a doctor's instructions. Caution is also advised when engaging in activities requiring alertness, such as driving or operating machinery, as dizziness or drowsiness may occur. Furthermore, this medication has many drug interactions, and the risk of side effects may increase depending on the other medications taken, so current medications must be disclosed to a doctor or pharmacist. In case of overdose, serious heart issues or decreased blood pressure may occur, requiring immediate emergency treatment. Lastly, capsules should be swallowed whole without opening or chewing.

• Rhinitis
• headache
• pharyngitis
• constipation
• increased cough
• influenza symptoms
• peripheral edema
• myalgia
• diarrhea
• vomiting

This medication should be stored in a tightly closed container to avoid exposure to air and light, and it is important to maintain a storage temperature between 1°C and 30°C. Maintaining appropriate temperature and container conditions is essential to safely preserve the drug's effectiveness.

Appearance

This is a round extended-release tablet, white to off-white in color.

Package unit

100 tablets (10 tablets/PTPX10), 500 tablets/bottle