BuKwang Dyurexan Tablet (Ziprasidone)

Adult dose

1. Hypertension Administer 20 mg of xipamide orally once daily after breakfast. For mild cases, administer 10 mg. When administered in combination with other antihypertensive agents, the initial dose should not exceed 20 mg per day. 2. Edema Administer 40 mg of this medicine orally once daily after breakfast. Reduce the dose to 20 mg per day according to the patient's response. In severe cases, up to 60 ∼ 80 mg may be administered as a single dose temporarily.

This medication should not be administered to patients with severe electrolyte imbalances. It should also not be used in patients with severely impaired liver function, especially those with hepatic coma. It is also not safe for patients with extremely poor kidney function, Addison's disease, or gout. Patients allergic to this medication or sulfonamide drugs should avoid taking it. Caution is advised when using this medication in patients with hyperuricemia or severe coronary arteriosclerosis or cerebral arteriosclerosis, as it may cause rapid diuresis, which increases the risk of blood concentration or thrombosis. Patients with prostatic enlargement may also experience urinary retention symptoms when taking this medication. The use of this medication may cause gastrointestinal symptoms such as vomiting, dry mouth, and occasionally abdominal pain, constipation, or diarrhea. Symptoms related to the mental and nervous system, such as headache, dizziness, fatigue, motor control disorders, drowsiness, and sometimes anxiety or fear, may also occur. Furthermore, hyperuricemia or gout may worsen, and there is a risk of worsening hyperlipidemia or diabetes. Care should be taken as sodium, magnesium, and chloride levels in the blood may decrease. There may be cardiovascular issues such as decreased heart function, orthostatic hypotension, and palpitations, and there is a risk of worsening kidney function or acute nephritis. Liver function abnormalities, jaundice, and rarely pancreatitis, cholecystitis, or cholelithiasis may also occur. Due to possible reductions in blood cell count or the occurrence of blood-related diseases, blood tests should be performed to monitor the condition. Skin rashes, itching, urticaria, and rare hypersensitivity to light may occur, along with muscle cramps or muscle tone abnormalities. If vision worsens, the patient should consult a physician immediately. Prolonged use may lead to low potassium levels, so potassium supplementation may be necessary. Especially elderly patients, those taking digitalis, patients experiencing vomiting or diarrhea, malnutrition, and patients with kidney and liver diseases need to be cautious. Hyponatremia may also occur and requires monitoring. Patients with diabetes or a tendency for gout should manage their blood sugar and uric acid levels closely, as this medication can exacerbate symptoms. There may be cross-reactivity with sulfonamide drugs, necessitating caution. This medication has many interactions with other drugs. It may reduce the effects of antidiabetic drugs and impair lithium excretion, increasing toxicity if taken together. When combined with some steroids, antibiotics, antihypertensives, cardiac glycosides, pain relievers, and others, side effects may increase or effectiveness may change. During pregnancy, reduced blood volume may affect the fetus, so it is advisable not to use it during the first three months of pregnancy. It is uncertain whether this medication is passed into breast milk, so if possible, it should be avoided or breastfeeding should be suspended. Finally, this medication is not recommended for children, as its safety and effectiveness in pediatric use have not been sufficiently established.

• Vomiting
• dry mouth
• abdominal pain
• constipation
• diarrhea
• headache
• dizziness
• fatigue
• ataxia
• drowsiness

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container in a cool, dry place. Proper storage can help maintain the medication's effectiveness over time.

Appearance

White round tablet

Package unit

30 tablets, 500 tablets/bottle