Myungin Phenytoin Tablet 100mg

Key information summary

Efficacy & effects

This medication is used to treat various types of seizures in patients with epilepsy, including tonic-clonic seizures (grand mal), focal seizures (partial), and psychomotor seizures. The injectable form is especially effective for status epilepticus and when oral seizure suppression is difficult, such as in cases of impaired consciousness or after surgery. It is also used for the treatment of digitalis-induced arrhythmia when first-line therapies are ineffective. This medication assists in controlling seizures and improving symptoms of arrhythmia.

Dosage

For oral administration as phenytoin, administer 100 mg three times a day as a single dose, with a maintenance dose divided into 300 to 400 mg per day. The dose can be increased to a maximum of 600 mg per day. For injectable use during status epilepticus, administer phenytoin sodium at 125 to 250 mg via slow intravenous injection at a rate not exceeding 50 mg/min, and if necessary, an additional 100 to 150 mg can be given 30 minutes later.

Precautions

This medication is indicated for the treatment of epilepsy, and patients and caregivers should closely monitor for mental health issues such as suicidal thoughts or behaviors, and depression that may arise during treatment. When administered by injection, inflammation, pain, or discoloration at the injection site may occur, and in severe cases, skin necrosis or tissue damage can happen, so caution is required. Patients who have hypersensitivity to this medication or have certain heart conditions or blood disorders should not take it, and it is essential to consult healthcare professionals when taking it in combination with other drugs due to potential changes in drug concentration or risk of side effects. Patients with impaired liver or kidney function, the elderly, and those with diabetes should use this medication cautiously, and treatment should be stopped immediately if severe skin reactions occur, consulting a doctor thereafter. Drowsiness, dizziness, and decreased motor ability may occur during treatment, so driving or operating hazardous machinery should be avoided, and dosage should be gradually reduced to prevent worsening seizures if stopping suddenly. Use during pregnancy may increase the risk of congenital malformations in the fetus, thus women who are planning to become pregnant or are pregnant must consult with their healthcare provider before taking this medication and should use effective contraception simultaneously. Regular monitoring of liver, kidney, blood tests, and vision tests is necessary, and maintaining appropriate dosing through drug concentration measurement is crucial. In case of overdose, severe symptoms such as coma, hypotension, and respiratory distress may arise, necessitating immediate emergency care.

Side effects

Urticaria, severe swelling (edema), skin rash, blisters, skin peeling, pain in oral/ocular mucosa, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), difficulty breathing, asthma attacks, respiratory distress accompanied by coughing and fever, yellowing of skin or eyes (jaundice), liver abnormalities (jaundice), sudden and severe headache, seizures, confusion, vision changes, paralysis, and a significant reduction in urine output.

Alternatives / Same-ingredient medications

• 

  Buhwang Phenytoin Capsule 100 mg

  Same ingredient
• 

  Hwanin Hidantoin Tablet (Phenytoin)

  Same ingredient

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