Tranexamic Acid Injection 500 mg

Adult administration

As tranexamic acid, administer 250-500 mg once or twice daily via intravenous or intramuscular injection. For bleeding during or after surgery, administer as needed 500-1000 mg intravenously or 500-2500 mg via slow intravenous infusion. Adjust dose according to age and symptoms.

This medication should be used cautiously when cutting the container for ampoule injection, as glass fragments may mix in, particularly when administered to children or the elderly. This medication should not be used in certain patients. For example, patients undergoing thrombin therapy, those with a history of thromboembolism, patients allergic to this medication or its components, and in cases of epidural or spinal administration. Caution is needed when administering to patients with thrombosis or at risk of thrombosis, patients who are bedridden for long periods post-surgery, patients with reduced kidney function, and those with specific blood coagulation disorders. Rarely, shock or allergic reactions may occur when this medication is administered, so patients should be closely monitored. If abnormal symptoms arise, administration should be stopped immediately and appropriate treatment must be given. Temporary visual disturbances or gastrointestinal symptoms, drowsiness, and headaches may occur as side effects, so if these symptoms worsen, it is advisable to consult a physician. There have been cases of seizures during administration in cardiovascular surgery, so care is needed, and if administered incorrectly epidurally or intrathecally, serious side effects may occur. When combined with other medications, the risk of thrombosis may increase, so it is essential to follow the physician's instructions, especially when used with medications related to blood coagulation. Caution is warranted when administering to pregnant women, as it can cross the placenta, and during breastfeeding, it has been reported to be passed through breast milk, but it is known not to have a significant effect on the infant. Elderly patients may have reduced body function, so special attention is required, such as adjusting the dosage. In cases of overdose, symptoms such as nausea, vomiting, and hypotension may occur, and in such cases, adequate hydration and support of kidney function is needed. This medication should be administered slowly via intravenous injection; if administered too quickly, symptoms such as nausea, chest discomfort, palpitations, and dizziness may occur. Finally, other injectable medications or hemostatic agents that may interact with this medication should be discussed with a professional before combined use.

Serious side effects

• Shock
• thromboembolism
• seizures.

Mild side effects

• Itching
• rash
• flushing
• temporary color vision disturbances
• nausea
• vomiting
• diarrhea
• drowsiness
• headache
• chest discomfort

This medication should be stored in a sealed container to prevent air and moisture from entering. This helps maintain the drug's efficacy over time and prevents deterioration.

Appearance

An ampoule containing a colorless clear liquid.

Package unit

10 ampoules/box [(5 milliliters/ampoule)]