Tranexamic Acid Injection 250 mg

Adult administration

As tranexamic acid, 250–500 mg per day divided into 1–2 intravenous or intramuscular injections. For bleeding during or after surgery, administer 500–1,000 mg intravenously or 500–2,500 mg via intravenous infusion as needed. Adjust dosage according to age and symptoms.

Care should be taken to avoid glass fragments when using the ampoule. Special caution is needed when children or the elderly use it. This medication should not be used in patients receiving thrombin, patients with thromboembolism, and patients with allergies to this medication or its components. Also, it should not be administered via intrathecal injection. Use with caution in patients with thrombosis or at risk of thrombosis, patients with bleeding disorders, patients who are bedridden after surgery, patients with impaired renal function, and specific blood coagulation disorders. When using this medication, it is important to monitor for rare occurrences of shock or allergic reactions, and if any abnormal symptoms appear, stop the administration immediately and seek appropriate treatment. Temporary visual disturbances, gastrointestinal symptoms, drowsiness, headache, etc. may occur. Caution is necessary as seizures have been reported during administration of this medication during cardiovascular surgery. There may also be serious side effects due to incorrect administration routes, so it must be administered correctly. Using this medication in combination with other drugs that can promote thrombosis may be risky, especially caution is needed when used together with anticoagulant medications or hormonal contraceptives. Patients using contraceptives are recommended to use non-hormonal alternative methods. During pregnancy, as this medication can cross the placenta, it should be used with caution, and while breastfeeding, although a small amount may pass into breast milk, it is expected to have little effect on the infant. Elderly patients may have decreased bodily functions, so it should be used with caution, such as reducing dosage. In case of overdose, symptoms like nausea, vomiting, and low blood pressure may occur, so it is important to stay hydrated and maintain kidney function. When administering, it should be injected slowly intravenously, as rapid injection may cause nausea, arrhythmias, low blood pressure, etc. This medication may undergo changes when mixed with certain other injections, so consult with a specialist before using together.

Serious side effects

• Shock
• thromboembolism
• renal failure
• hematuria
• seizures
• convulsions.

Mild side effects

• Itching
• rash
• flushing
• temporary color vision disturbances
• nausea
• vomiting
• diarrhea
• drowsiness
• headache
• chest discomfort

Store this medication in a sealed container to prevent exposure to air or moisture. This will help maintain the drug's efficacy for a longer period.

Appearance

An ampoule containing a colorless, clear solution.

Package unit

50 ampoules/box [5 milliliters/ampoule], 10 ampoules/box [5 milliliters/ampoule]