Crownac Tablet (Clonixin Lysine)

Adult dose

Adults: Administer 125∼250 mg of clonixin lysinate orally 3 times daily.

People who regularly consume more than three glasses of alcohol daily should consult a doctor or pharmacist before taking this medication. Individuals who consume a lot of alcohol may have an increased risk of gastrointestinal bleeding when taking this medication. This medication may increase the risk of cardiovascular diseases. The risk of cardiovascular issues such as myocardial infarction and stroke may be heightened, so patients with cardiovascular diseases or risk factors should exercise particular caution. If symptoms of cardiovascular issues occur, medical attention should be sought immediately, and it is important to be well-informed about symptoms and coping methods in advance. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation. Elderly patients or those receiving treatment for prolonged periods may have a higher risk, so it is crucial to monitor gastrointestinal symptoms carefully during use. This medication should not be taken by patients with peptic ulcers, those who have had problems with their stomach or duodenum due to medications, and individuals allergic to this medication or its components. Those who have had allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should also avoid it. Pregnant women or women who may become pregnant, and patients with severe liver impairment, kidney impairment, or heart failure should not use this medication. Combining this medication with other non-steroidal anti-inflammatory drugs, ACE inhibitors, angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, and warfarin may increase risks; thus, these combinations should be avoided or discussed with a physician. Patients with a history of peptic ulcers, elderly patients, patients with hypertension, heart failure patients, patients with bronchial asthma, and individuals with liver or kidney dysfunction should consult a doctor or pharmacist before taking this medication. It is advisable to avoid breastfeeding during the use of this medication, as drugs can pass into breast milk and cause adverse reactions in infants. If symptoms such as nausea, vomiting, diarrhea, abdominal pain, skin rash, anemia, liver dysfunction, drowsiness, or headache occur during treatment, discontinue use immediately and consult a physician. This medication should be used at the lowest effective dose for the shortest duration possible, and regular check-ups and monitoring for adverse reactions are necessary when treating chronic conditions. During use, caution should be exercised for serious side effects such as gastrointestinal bleeding, cardiovascular issues, kidney and liver dysfunction, and skin rashes; if these symptoms appear, consult a healthcare provider immediately.

• Gastrointestinal bleeding
• serious cardiovascular thrombotic events
• myocardial infarction
• stroke
• bleeding of the stomach or intestines
• ulcers
• perforation
• nausea
• vomiting
• diarrhea

Drug interactions

Do not use this medication together with non-steroidal anti-inflammatory drugs, ACE inhibitors, angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, coumarin anticoagulants, cyclosporine, tacrolimus, antiplatelet agents, selective serotonin reuptake inhibitors, or corticosteroids. Consult a physician or pharmacist when using it in combination with misoprostol, a treatment for peptic ulcers.

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature to safely preserve the drug's effectiveness.

Appearance

Light blue round film-coated tablet

Package unit

10 tablets/PTP