Medication info

Daewon Ascorbic Acid Injection 500mg

Prescription medicationInjections정맥
Ingredient · strength
Ascorbic Acid›250mg / 1mL
Manufacturer / importer
대원제약(주)
Appearance
A brown ampoule injection containing a colorless to pale yellow liquid.
Packaging
For domestic use: 2mL/ampoule X 50, for export: 2mL/ampoule X 50.
Approval status
Active

MFDS item code 198400650 · Notified 1984.02.23 · Insurance code 671800541

Summary

Main use
Prevention and treatment of vitamin C deficiency, improvement of capillary hemorrhage, etc.
Who receives it
Adults
Adult administration
As ascorbic acid, administer 50-1,000mg once to several times daily via subcutaneous, intramuscular, or intravenous injection. Adjust dosage according to age and symptoms.

Ingredients

Manufacturer
대원제약(주)

Efficacy & effects

Prevention and treatment of vitamin C deficiency, improvement of capillary hemorrhage, etc.

  • Vitamin C deficiency
  • scurvy
  • capillary hemorrhage
  • nasal bleeding
  • gingival bleeding
  • hematuria
  • chloasma
  • freckles
  • post-inflammatory hyperpigmentation
  • photosensitivity dermatitis.
View approved original text

This medication is used to prevent and treat vitamin C deficiency in cases of acute conditions or when oral administration is difficult. It improves conditions like scurvy and is helpful in situations where the demand for vitamin C increases, such as in pregnant women, lactating mothers, and during intense physical labor. It is also effective in promoting osteoid formation and bone union during fractures, and can be used to alleviate skin issues such as chloasma, freckles, post-inflammatory hyperpigmentation, and photosensitivity dermatitis. Overall, this product is useful for improving vitamin C deficiency and related metabolic disorders.

How it is given

Adult administration

As ascorbic acid, administer 50-1,000mg once to several times daily via subcutaneous, intramuscular, or intravenous injection. Adjust dosage according to age and symptoms.

Precautions

This medication can introduce glass fragments when opening the injection container, so care must be taken during use. Extra caution is required when being used by children or the elderly. This medication contains sodium bisulfite, which can cause serious allergic reactions or asthma attacks in individuals who are allergic to sulfites, so it should be used cautiously. Patients with asthma should be especially careful. This medication should not be used in certain patients. For example, individuals allergic to this medication or its components, patients with oxalate nephropathy or Mediterranean anemia, gout or cystinuria patients, G6PD deficiency patients, and those with renal oxalate stones should not be administered this drug. While using this medication, side effects such as nausea, vomiting, diarrhea, abdominal pain, cramps, fatigue, flushing, headache, insomnia may occur. Administering more than 1 gram per day can acidify urine, increasing the risk of diarrhea or kidney stones. Taking more than 600 milligrams a day can lead to diuretic effects, and hemolysis may occur in G6PD deficiency patients. Excessive dosage can precipitate oxalate or urate in the urinary tract, so caution is warranted. This medication is generally taken orally, but injections should only be used in acute conditions or when oral administration is challenging, and switching to oral administration is advisable when possible. This medication can interact with other drugs. Salicylates may impair the absorption of this drug, and using it with aspirin, nicotine, alcohol, some appetite suppressants, iron supplements, certain anticonvulsants, oral contraceptives, and tetracycline antibiotics may diminish its effectiveness, so concurrent use should be avoided. Additionally, high-dose administration may reduce the effects of some anticoagulants and can interact with certain psychiatric medications. During pregnancy, the effects on the fetus are unclear, so this medication should only be administered when the benefits outweigh the risks, and high doses exceeding 1 gram should be avoided. While breastfeeding, this medication can pass into breast milk, but it is known to be non-harmful to infants at typical doses. This medication may affect the results of certain clinical tests, potentially yielding false results in urine glucose tests, hematuria tests, and occult blood tests in stool. Overdosage can lead to diarrhea or kidney stones, and diuretic effects may manifest with doses exceeding 600 milligrams daily, so dosing should be stopped immediately if symptoms appear and appropriate treatment should be sought. When administered via injection, temporary pain may occur at the injection site, and injections should be administered with minimal volume, avoiding nerve regions. If pain or blood reflux is experienced when injecting, the needle should be removed immediately, and intravenous injections should be administered slowly to reduce dizziness or vascular pain. Finally, this medication should be kept out of the reach of children and stored in a dry place away from direct sunlight. Transferring the medication to another container may lead to misuse or degradation of quality, so it should always be stored in its original container with the lid tightly closed.

Side effects and when to seek care immediately

Serious side effects

Sulfite anaphylaxis (severe allergic reaction), asthma attacks (breathing problems), hemolysis (possible in patients with G6PD deficiency), increased risk of kidney stones, diarrhea and kidney stone risk (when administered exceeding 1 gram per day).

Mild side effects

Nausea, vomiting, diarrhea, abdominal pain, fatigue, flushing, headache, insomnia, temporary mild pain at the injection site, dizziness, vascular pain.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a sealed container that can block light. Additionally, it is important to maintain a room temperature between 1 and 30 degrees Celsius during storage. This way, the effectiveness of the medication can be preserved over time.

Appearance and packaging

Appearance

A brown ampoule injection containing a colorless to pale yellow liquid.

Package unit

For domestic use: 2mL/ampoule X 50, for export: 2mL/ampoule X 50.

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.