Medication info

Jeil Epinephrine Injection

Prescription medicationInjections주사
Ingredient · strength
Epinephrine›1mg / 1mL
Manufacturer / importer
(주)제일제약
Appearance
A brown transparent ampoule containing a colorless transparent solution. This medication slowly turns light red and subsequently brown upon exposure to air or light.
Packaging
1mL × 10 ampoules, 1mL × 50 ampoules
Approval status
Active

MFDS item code 198400285 · Notified 1984.11.14 · Insurance code 650500421

Summary

Main use
Relief of symptoms of bronchial asthma attacks and serum sickness (urticaria, angioedema)
Who receives it
Adults
Adult administration
1. Subcutaneous and intramuscular: Administer 0.2-1.0mL as epinephrine per dose. 2. Intravenous injection: In emergencies such as cardiac arrest, dilute this medication (not exceeding 0.25mL) with normal saline and administer slowly. 3. When combined with local anesthetics: Add 1-2 drops of this medication per 10mL of local anesthetic for use.

Ingredients

Manufacturer
(주)제일제약

Efficacy & effects

Relief of symptoms of bronchial asthma attacks and serum sickness (urticaria, angioedema)

  • Bronchial asthma attacks
  • serum sickness
  • urticaria
  • angioedema
  • drug-induced shock
  • cardiac arrest
View approved original text

This medication is used to relieve bronchial asthma attacks and the symptoms of serum sickness, urticaria, and angioedema. It also assists in the emergency treatment of drug-induced shock and cardiac arrest and is effective in prolonging the effects of local anesthetics. Therefore, it plays a crucial role in various acute allergic reactions and emergency situations.

How it is given

Adult administration

1. Subcutaneous and intramuscular: Administer 0.2-1.0mL as epinephrine per dose. 2. Intravenous injection: In emergencies such as cardiac arrest, dilute this medication (not exceeding 0.25mL) with normal saline and administer slowly. 3. When combined with local anesthetics: Add 1-2 drops of this medication per 10mL of local anesthetic for use.

Precautions

This medication can be contaminated with glass fragments when using ampoules, so care must be taken to minimize glass contamination, especially when using it on children and the elderly. It should not be administered to patients with certain conditions such as atherosclerosis, heart diseases, hypertension, hyperthyroidism, diabetes, or angle-closure glaucoma. Moreover, it should be given cautiously only when necessary in patients with chronic bronchial asthma, ischemic heart disease, pregnant women, children, and the elderly. When administering this medication, it is important to carefully monitor the patient's cardiac and respiratory status, and if any abnormal symptoms such as palpitations, arrhythmias, or breathing difficulties occur, administration should be stopped immediately and appropriate measures should be taken. This medication can interact with other drugs, so serious side effects may occur when used in combination, and it should only be used after consulting with a healthcare professional. Pregnant or breastfeeding women should avoid using this medication, especially during pregnancy, due to the risk of fetal hypoxia. Children and the elderly may be more sensitive to this medication, so it is advisable to start with a small dose and observe symptoms before careful administration. In case of overdose, serious cardiac and vascular problems may occur, so it is essential to strictly adhere to the prescribed dosage and method. This medication is easily deteriorated by light, air, and heat, so it should be stored in a container that blocks light at a temperature below 25 degrees Celsius, and refrigeration should be avoided.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction. High fever with severe rash, blisters, exfoliation of skin, pain in mucous membranes of mouth/eyes → severe skin adverse reactions. Difficulty breathing → respiratory problems. Cardiac arrest, ventricular fibrillation, sudden hypertension, cerebral hemorrhage, pulmonary edema → serious circulatory system adverse reactions. Sudden and severe headache, seizures, confusion, visual disturbances.

Mild side effects

  • Palpitations
  • stress-induced cardiomyopathy
  • chest pain
  • tachycardia
  • arrhythmias
  • facial flushing
  • pallor
  • elevated blood pressure
  • headache
  • dizziness
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  • anxiety
  • tremors
  • memory impairment
  • psychomotor agitation
  • nausea
  • vomiting
  • pigmentation of eyelids and conjunctiva
  • nasal pigmentation
  • macular edema
  • minor bleeding
  • vasospasm
  • conjunctival injection
  • eye pain
  • corneal pigmentation
  • localized necrosis at injection site
  • peripheral ischemia
  • warmth
  • sweating
  • limb coldness
  • hypersensitivity
  • hyperglycemia.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a light-protective sealed container, and it is important to maintain a temperature below 25 degrees Celsius. It should not be stored in a refrigerator to maintain its effectiveness.

Appearance and packaging

Appearance

A brown transparent ampoule containing a colorless transparent solution. This medication slowly turns light red and subsequently brown upon exposure to air or light.

Package unit

1mL × 10 ampoules, 1mL × 50 ampoules

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.