Hepamelz Injection (L-Aspartic Acid-L-Ornithine)

Adult administration

For patients with severe liver disease, administer L-Aspartic Acid-L-Ornithine intravenously at a dose of 2g (4 ampoules) daily for 7 days.

This medication is provided in a glass ampoule form, so care must be taken to avoid glass fragments when cutting the container. Particularly cautious administration is required for children and the elderly. This medication should not be used in patients with certain conditions. For example, it should be avoided in patients with lactic acidosis, methanol poisoning, fructose-sorbitol intolerance, fructose-1,6-diphosphatase deficiency, and severe renal impairment. As this medication contains sodium pyrosulfite, it may cause allergic reactions or asthma attacks in individuals sensitive to sulfites, especially asthma patients. Administration of this medication may sometimes lead to sensations of warmth at the back of the head, nausea, gastric discomfort, and vomiting. During high-dose administration, blood or urine urea levels should be checked for abnormality. If liver function is poor, the infusion rate should be adjusted to reduce discomfort or vomiting. This medication should be administered slowly intravenously, as rapid administration may increase the risk of side effects.

Serious side effects

Asthma attack, severe allergic reactions such as sulfite anaphylaxis

Mild side effects

• Warm sensation in the occiput
• nausea
• gastric discomfort
• vomiting

This medication should be stored in a sealed container and kept at room temperature between 1 to 30 degrees Celsius. Storing it this way will ensure the medication's effectiveness is safely maintained.

Appearance

Brown glass ampoules containing a colorless and transparent liquid

Package unit

10 ampoules/box [(5 milliliters/ampoule)]