Medication info
BuKWANG Isosorbide Sustained-Release Capsule (Isosorbide Dinitrate Sustained Granule)

BuKWANG Isosorbide Sustained-Release Capsule (Isosorbide Dinitrate Sustained Granule)

Prescription medicationOral
Ingredient · strength
Isosorbide Dinitrate Sustained-Release Granules›83.8mg / 1 capsule
Manufacturer / importer
BuKWANG Pharmaceutical Co., Ltd.
Appearance
A capsule with a blue upper part and a colorless transparent lower part containing whitish pellets.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 198300603 · Approved 1983.07.05 · Insurance code 642200970

Summary

Main use
Adjunctive treatment for ischemic heart disease (angina, myocardial infarction, etc.) and congestive heart failure
Who takes it
Adults
Adult dose
Adults: Take 20 mg of isosorbide dinitrate orally twice daily. If a dose increase is needed, the dose may be increased to 40 mg per administration. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
BuKWANG Pharmaceutical Co., Ltd.

Efficacy & effects

Adjunctive treatment for ischemic heart disease (angina, myocardial infarction, etc.) and congestive heart failure

  • Angina pectoris
  • myocardial infarction
  • coronary sclerosis
  • chronic ischemic heart disease
  • asymptomatic ischemic heart disease
  • atherosclerotic heart disease
  • congestive heart failure
View approved original text

This medication is used to treat heart diseases such as angina pectoris, myocardial infarction, chronic ischemic heart disease, and atherosclerotic heart disease. Additionally, it helps improve cardiac function in conjunction with cardiac glycosides or diuretics as adjunctive therapy for congestive heart failure.

How to take

Adult dose

Adults: Take 20 mg of isosorbide dinitrate orally twice daily. If a dose increase is needed, the dose may be increased to 40 mg per administration. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication has a vasodilating effect. It should not be used in patients with very low blood pressure or in a state of acute cardiac function decline. In particular, patients with acute heart problems or in shock, glaucoma patients, and those allergic to this medication or similar drugs should not receive it. Additionally, this medication contains lactose, so it should be avoided in patients with certain genetic metabolic disorders such as lactose intolerance. Patients with low blood pressure, pulmonary hypertension, certain valvular heart diseases, and orthostatic hypotension should use this medicine with particular caution. While taking this medication, side effects such as dizziness, headache, palpitations, and gastrointestinal disturbances may occur, so if symptoms are severe, consult your doctor. Furthermore, this medication may cause blood pressure to drop too low when taken with other antihypertensive drugs, erectile dysfunction medications, or alcohol; caution is needed when used together. Women who are pregnant or breastfeeding should definitely consult with their doctor before using this medication, especially in early pregnancy, should avoid using it if possible. The safety in children has not been established, so it is advisable not to use it in children. Elderly patients should use it cautiously as drug concentration may increase due to decreased liver function. For sustained-release formulations, the capsules should be swallowed whole and not chewed or crushed; otherwise, side effects such as headaches may occur. Finally, this medication is not suitable for emergency treatment of acute angina and caution should be exercised as therapeutic effects may decrease with prolonged high-dose use.

Side effects

  • Dizziness
  • heat sensation
  • flushing
  • palpitations
  • hypotension
  • edema
  • bradyarrhythmia
  • syncope
  • exacerbation of angina
  • headache
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  • heaviness in the head
  • staggering
  • tinnitus
  • weakness
  • discomfort
  • drowsiness
  • nausea
  • vomiting
  • diarrhea
  • abdominal discomfort
  • upper abdominal pain
  • loss of appetite
  • rash
  • increased AST
  • increased ALT
  • red rash
  • allergic reaction
  • desquamative dermatitis
  • methemoglobinemia

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly sealed container to prevent exposure to air and moisture. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. This helps to preserve the medication's effectiveness and safety for a longer period.

Appearance and packaging

Appearance

A capsule with a blue upper part and a colorless transparent lower part containing whitish pellets.

Package unit

30 capsules/bottle, 100 capsules/bottle

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.