Burufen Tablet 400 milligrams (Ibuprofen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue injury, non-articular rheumatic diseases, acute gout, psoriatic arthritis: Take 200-600mg orally 3-4 times per day. The maximum daily dose can be up to 3200mg. 3. Mild to moderate pain, cold symptoms: Take 200-400mg orally 3-4 times per day. Adjust according to age and symptoms.

Child dose

2. Juvenile rheumatoid arthritis: Administer 30-40mg per kg of body weight orally 3-4 times a day.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks per day, so it is essential to consult with a healthcare professional or pharmacist. Prolonged use or use in individuals at risk for cardiovascular disease may increase the likelihood of serious cardiovascular issues such as myocardial infarction or stroke, so caution is necessary. Serious adverse reactions such as gastrointestinal bleeding, ulcers, and perforations may occur, especially in the elderly or those who take the medication long-term. Individuals with a history of gastrointestinal ulcers or bleeding, or severe liver, kidney, or heart dysfunction should not take this medication. People with a history of bronchial asthma or hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs should also avoid taking this medication. In late pregnancy, this medication should not be taken as it may lead to early closure of the ductus arteriosus in the fetus. After mid-pregnancy, kidney dysfunction or oligohydramnios may occur, necessitating prenatal monitoring. Do not exceed the recommended dosage and avoid taking it with other non-steroidal anti-inflammatory drugs. For nursing mothers, this medication can be transmitted through breast milk and may cause serious adverse reactions in infants, so consideration should be given to stopping breastfeeding or the medication. Caution is also needed when driving or operating machinery as this medication may slow down reaction times, and combining it with alcohol may exacerbate such effects. Individuals with blood abnormalities, liver or kidney disease, heart disease, hypertension, or a history of hypersensitivity should consult a healthcare professional before use. This medication may interact with certain drugs, therefore caution is required for patients taking ACE inhibitors, lithium, diuretics, methotrexate, anticoagulants, and selective serotonin reuptake inhibitors. If severe allergic reactions, skin rashes, difficulty breathing, bleeding, liver dysfunction, or decreased kidney function occur while taking this medication, discontinue immediately and consult a healthcare professional. Regular blood tests and assessments of liver and kidney function should be performed during long-term use, and if any abnormal symptoms are detected, discontinuation or adjustment of the medication is necessary. This medication is intended for symptomatic relief and should be taken for the shortest duration and at the lowest effective dose for safety. In case of overdose, symptoms such as dizziness, nausea, vomiting, liver dysfunction, and kidney failure may occur, requiring immediate medical attention. Keep out of reach of children and store in its original container to prevent misuse or deterioration in quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), high fever with severe rash, blisters, painful mucous membranes of the mouth/eyes (severe skin adverse reaction), asthma attacks, difficulty breathing, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue (liver dysfunction), sudden and severe headache, seizures, altered consciousness.

Mild side effects

Nausea, vomiting, abdominal pain, indigestion, diarrhea, headache, dizziness, drowsiness, lightheadedness, rash, itching, fatigue, fever, epistaxis (nosebleeds), swelling (edema), low blood pressure, high blood pressure, palpitations, heart failure, blood disorders (anemia, thrombocytopenia, etc.), liver function abnormalities (elevated GOT, GPT, ALP)

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs, low-dose aspirin, or high doses of methotrexate. Consult your doctor or pharmacist when taken with ACE inhibitors, lithium, furosemide and thiazide diuretics, anticoagulants (such as warfarin), and selective serotonin reuptake inhibitors.

Food interactions

Do not take this medication with alcohol.

Store this medication in a tightly sealed container to prevent air or moisture from entering, and it is recommended to keep it at a cool room temperature. Avoid extremely hot or cold places, and store away from direct sunlight.

Appearance

White rectangular film-coated tablet

Package unit

10 tablets/blister × 2