Han-in Imipramine Hydrochloride 25 mg

Adult dose

1. Depression, depressive states Adults: The initial dose is 25-75㎎ per day as imipramine hydrochloride, administered orally in divided doses, and gradually increased up to 200㎎. If necessary, the dose may be increased up to 300㎎.

Child dose

2. Enuresis 1) Children: 25-50㎎ per day of this drug, administered in 1-2 divided doses. 2) Infants: 25㎎ once daily.

This medication may increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults with major depressive disorder or other psychiatric disorders, so careful evaluation by a physician is necessary before use. This medication should not be used in patients with certain conditions such as glaucoma, early recovery from myocardial infarction, prostate disease, arrhythmia, acute delirium, and pyloric stenosis. It should be used cautiously in patients with difficulty urinating, heart diseases, epilepsy, bipolar disorder, liver and kidney disorders, hypotension, and chronic constipation, especially starting with a low dose in elderly patients is important. During treatment, there may be side effects such as suicidal tendencies, changes in mental symptoms, cardiovascular issues, dry mouth, constipation, and urinary difficulties due to anticholinergic effects, so careful monitoring is required. Pregnant women or those who may become pregnant are advised not to take this medication, and breastfeeding should be discontinued if the mother is on this medication. In case of overdose, symptoms such as central nervous system effects, heart issues, and respiratory depression may occur, and immediate medical attention is required, as there is no specific antidote; supportive treatment according to symptoms is needed. This medication may interact with other drugs, so if you are taking any other medications, it is essential to inform your physician or pharmacist, particularly not to use it in conjunction with MAO inhibitors. While taking this medication, drowsiness or decreased concentration may occur, so it is advisable to avoid driving or operating dangerous machinery. Abrupt discontinuation of this medication can lead to symptoms such as anxiety and nervousness, so it is necessary to taper off gradually as directed by a physician. Keep out of reach of children and do not transfer to other containers.

• Movement paralysis
• severe muscle stiffness
• dysphagia
• tachycardia
• changes in blood pressure
• sweating
• fever
• leukocytosis
• elevated serum CPK
• myoglobinuria

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best kept at room temperature. Keeping it at a typical indoor temperature that is neither too warm nor too cold will help maintain the efficacy of the medication.

Appearance

Green round film-coated tablet

Package unit

300 tablets/bottle