
Key information summary
Efficacy & effects
This medication is used for the treatment of depression.
Dosage and Administration
The initial dose of trazodone hydrochloride is 150 mg taken orally once daily and increased by 50 mg every 3 to 4 days. Outpatients should not exceed 400 mg per day, and hospitalized patients (with severe depression) should not exceed 600 mg per day. This medication must be taken after meals or snacks. A minimum effective dose should be maintained, and if the maximum therapeutic effect is achieved at that dose, it should be gradually reduced based on symptoms.
Precautions
This drug is primarily used as an antidepressant to treat symptoms associated with depression. While taking this medication, there may be a risk of dangerous behaviors such as suicidal thoughts or attempts, so young patients, especially those between 18 and 24 years old, should be monitored more closely. If prolonged erection occurs, stop taking the medication immediately and consult a doctor. This drug should not be used in specific patients, such as those with allergies to this drug or its components, patients taking MAO inhibitors, children under 18 years old, patients with acute myocardial infarction, patients with alcohol or sedative addiction, and certain genetically lactose-intolerant patients. Special caution is needed when administering this drug to patients with heart disease or impaired liver or kidney function, patients with glaucoma or urinary disorders, patients with a predisposition to bipolar disorder or psychosis, and elderly patients. This drug can cause serious adverse reactions such as neuroleptic malignant syndrome, blood disorders, and cardiovascular and neuropsychiatric side effects, so if symptoms occur, consult medical staff immediately. Drowsiness or impaired concentration may occur during treatment, so driving or operating dangerous machinery should be avoided. Moreover, this drug may interact with other medications, so if you are taking other drugs, be sure to inform your doctor or pharmacist. Women who are pregnant or breastfeeding should exercise caution when taking this medication, and if breastfeeding, it is advisable to either avoid taking the medication or to discontinue breastfeeding if possible. Finally, this medication is not used in children as its safety and efficacy have not been established, and elderly patients may need to adjust the dosage due to declining bodily functions. Sudden discontinuation of this medication may lead to withdrawal symptoms, so it's important to taper off gradually according to a doctor's instructions. Store this medication out of reach of children and do not transfer it to another container as this helps maintain quality.
Side effects
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever, severe rash, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urine output


