Summary
- Main use
- Treatment of hypertension with normal renal function, congestive heart failure, and cirrhosis with ascites
- Who takes it
- Adults
- Adult dose
- This medicine may be administered alone, but concomitant use with a thiazide or potassium-excreting diuretic is preferable. ○ Adults 1. Congestive heart failure: Administer 5-10㎎ of amiloride hydrochloride orally daily. 2. Hypertension: Administer 5-10㎎ of this medicine daily in combination with an antihypertensive. 3. Cirrhosis with ascites: Administer a low dose of 5㎎ of this medicine daily in combination with a low dose of another diuretic. Adjust the dose as appropriate according to age and symptoms.
Ingredients
- Manufacturer
- Gunil Pharmaceutical Co., Ltd.
Efficacy & effects
Treatment of hypertension with normal renal function, congestive heart failure, and cirrhosis with ascites
- Congestive heart failure
- hypertension
- cirrhosis with ascites
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Used for conditions such as congestive heart failure, hypertension with normal kidney function, and ascites associated with cirrhosis.
How to take
Adult dose
This medicine may be administered alone, but concomitant use with a thiazide or potassium-excreting diuretic is preferable. ○ Adults 1. Congestive heart failure: Administer 5-10㎎ of amiloride hydrochloride orally daily. 2. Hypertension: Administer 5-10㎎ of this medicine daily in combination with an antihypertensive. 3. Cirrhosis with ascites: Administer a low dose of 5㎎ of this medicine daily in combination with a low dose of another diuretic. Adjust the dose as appropriate according to age and symptoms.
Precautions
This medication should not be used in patients with hyperkalemia who have a serum potassium level of 5.5 mmol/L or higher. Additionally, it should be avoided in patients taking potassium-sparing drugs or potassium supplements. It is not safe for use in anuric patients or those with acute or chronic renal failure, as well as patients with severe progressive kidney disease. Patients with diabetic nephropathy or a history of hypersensitivity to this drug should also not be treated with it. This medication contains lactose, so it should not be used in patients with genetic problems such as lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Caution is warranted when administering this drug to patients with diabetes, metabolic or respiratory acidosis, electrolyte imbalances, reversible hematuria, cirrhosis, and impaired kidney function. Various side effects can occur when taking this medication, including headache, fatigue, myalgia, dyspepsia, elevated potassium levels, skin rash, dizziness, shortness of breath, visual disturbances, and urination problems. Particularly for diabetic patients, kidney function tests should be performed early in treatment to minimize the risk of hyperkalemia, and patients with hematuria or high serum creatinine levels should be monitored regularly. This drug may interact with lithium, other diuretics, ACE inhibitors, potassium-containing foods, non-steroidal anti-inflammatory drugs (NSAIDs), and metformin, so caution is advised when taking it together. During pregnancy, side effects can occur in the fetus and newborn, so it should only be administered when absolutely necessary, and caution is advised regarding breastfeeding, where avoidance or cessation of breastfeeding is recommended. Finally, the safety and efficacy of this drug in pediatric patients has not been sufficiently established, so it is advisable not to use it in children.
Side effects
- Headache
- weakness
- fatigue
- abdominal pain
- neck pain
- limb pain
- angina
- orthostatic hypotension
- arrhythmia
- palpitations
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- complete heart block
- loss of appetite
- nausea
- vomiting
- diarrhea
- constipation
- abdominal pain
- gastrointestinal bleeding
- jaundice
- thirst
- indigestion
- abdominal bloating
- gastrointestinal disorders
- heartburn
- elevated serum potassium levels
- hyponatremia
- itching
- rash
- dry mouth
- alopecia areata
- muscle cramps
- joint pain
- dizziness
- paresthesia
- tremors
- brain disorders
- nerve hyperactivity
- mental confusion
- insomnia
- decreased libido
- depression
- drowsiness
- cough
- shortness of breath
- nasal congestion
- visual disturbances
- increased intraocular pressure
- tinnitus
- erectile dysfunction
- polyuria
- urination disorders
- bladder spasms
- frequent urination
- gynecomastia
Not everyone experiences these, and they can vary from person to person.
Storage
This medication should be stored in a tightly closed container to prevent exposure to air or moisture. This helps maintain the effectiveness of the medication and prevents deterioration.
Appearance and packaging
Appearance
Yellowish circular tablet.
Package unit
100 tablets/bottle, 1000 tablets/bottle
Questions about this medicine
No questions yet.
For anything that needs medical judgment, consult a doctor or pharmacist.
