Herben Tablet (Diltiazem Hydrochloride)

Adult dosage

(Oral: extended-release capsules) Adults: Administer 180㎎ of diltiazem hydrochloride orally once daily. Depending on symptoms, the dose may be increased to 360㎎ per dose. Elderly patients and patients with hepatic or renal impairment: Administer 90-120㎎ once daily as the initial dose. Monitor the heart rate during treatment and do not increase the dose if it falls to 50 beats or less. The dose may be adjusted according to age and symptoms. (Oral: extended-release tablets 30㎎) Adults: Administer 30-60㎎ of diltiazem hydrochloride orally per dose, 3 times daily. The dose may be adjusted according to age and symptoms. (Oral: extended-release tablets 90㎎) Adults: Administer 90㎎ of diltiazem hydrochloride orally per dose, 2 times daily. If necessary, the dose may be increased to 90-180㎎ per dose. The dose may be adjusted according to age and symptoms. (Injection) Dissolve this medication in at least 5㎖ of normal saline injection or dextrose injection and administer as follows. 1. Tachyarrhythmia (supraventricular) Adults: Slowly inject 10㎎ of diltiazem hydrochloride intravenously over approximately 3 minutes per dose. 2. Emergency treatment of abnormal hypertension during surgery ① Bolus intravenous injection Adults: Slowly inject 10㎎ intravenously over approximately 1 minute per dose. ② Intravenous infusion Adults: Infuse 5-15㎍ per ㎏ of body weight intravenously over 1 minute. After lowering blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. 3. Hypertensive emergency (hypertensive crisis) Adults: Infuse 5-15㎍ per ㎏ of body weight intravenously over 1 minute. After lowering blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. The dose may be adjusted according to age and symptoms.

This medication should not be used in patients with severely impaired heart function or in those with specific cardiac conduction disorders. Patients with severe hypotension or in shock, as well as those allergic to this medication, should not receive it. Caution is advised for women who are pregnant or may become pregnant, and certain patients with heart disease. It should be used with caution in patients with congestive heart failure or significantly impaired liver and kidney function. Various side effects such as headache, constipation, cough, edema, vomiting, and insomnia may occur while taking this medication. Cardiac side effects may include bradycardia, arrhythmia, and blood pressure decrease, so treatment should be stopped immediately if abnormal symptoms occur. Diverse side effects may manifest in various parts of the body, including mental symptoms or gastrointestinal, skin, respiratory, and urogenital systems, thus consultation with a healthcare professional is recommended if symptoms arise. Abrupt discontinuation of this medication may worsen symptoms, so dosage should be gradually reduced and monitored. Patients with weak cardiac function or hypotension are at risk of worsening kidney function, hence regular kidney function tests are essential. Caution is necessary when taking this medication with other drugs, particularly heart medications, antiarrhythmics, or antihypertensives. It is advisable that women who are pregnant or breastfeeding do not use this medication; if unavoidable, breastfeeding should be discontinued. The safety for children has not been established, so it should be administered with caution in pediatric cases. In case of overdose, serious heart problems and low blood pressure can occur, requiring immediate emergency treatment and medical supervision. For capsule formulations, the capsules should be swallowed whole without opening or chewing.

• Rhinitis
• headache
• pharyngitis
• constipation
• increased cough
• influenza symptoms
• peripheral edema
• myalgia
• diarrhea
• vomiting

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at room temperature between 1 degree and 30 degrees Celsius.

Appearance

White round tablet

Package unit

100 tablets (10 tablets/PTPX10), 500 tablets/bottle