Hyun's Lidocaine Hydrochloride Injection 2%

Adult administration

(Solution: 2% Viscosity) The maximum single dose of lidocaine hydrochloride should not exceed 4.5 mg per kg body weight, and the total dosage should not exceed 300 mg (15 mL of this drug). For symptomatic treatment of oral and pharyngeal mucosa irritation and inflammation, administer 300 mg (15 mL) of lidocaine hydrochloride. In oral use, hold the drug in the mouth and spit it out; during pharyngeal use, hold it and swallow. Readministration is prohibited within 3 hours and should not exceed 8 times in 24 hours.

This drug is a glass ampule injectable solution, so care must be taken when cutting the container to avoid the introduction of glass fragments. Special caution is needed when used in children or the elderly. This drug should not be used in certain patients. For example, it should not be administered to patients with severe bleeding or in a state of shock, patients with inflammation at the injection site or septicemia, and patients allergic to this drug or similar local anesthetics. Caution is advised when administering to patients with central nervous system diseases, pregnant women, elderly individuals, patients with severe hypertension, and those with severe spinal deformities. This medication can rarely cause serious side effects such as shock, hypotension, and respiratory depression; therefore, the patient's condition should be closely monitored. Additionally, malignant hyperthermia may occur rarely, characterized by a rapid increase in body temperature, muscle rigidity, and arrhythmias. If such symptoms appear, administration should be stopped immediately and appropriate treatment provided. Since this medication affects the central nervous system, symptoms like tremors, seizures, drowsiness, dizziness, and nausea may occur, so appropriate measures should be taken immediately upon noticing such symptoms. When using this drug, allergic reactions may manifest as hives or edema, requiring caution, and in severe cases, anaphylaxis may occur. Before use, it is essential to check the patient's overall condition carefully and to use the lowest concentration and minimum dosage possible. Care should be taken to use only small amounts when injecting into vascular areas, ensuring that the injection needle does not enter a blood vessel. When used in conjunction with vasoconstrictors, the risk of side effects may be increased in certain patients, so careful consideration of its administration is necessary. This medication should only be administered to pregnant women or women of childbearing potential when the benefits outweigh the risks. Elderly patients may experience slower metabolism of this drug, making side effects more likely, so dosage adjustment and condition monitoring are required. This medication is not for ophthalmic use and careful attention must be paid as long-term use at high concentrations may pose a carcinogenic risk. Additionally, this medication should be administered cautiously in patients with severely impaired liver and kidney function or cardiac conduction disorders, avoiding overdose and frequently monitoring blood pressure and electrocardiography. Caution is needed when combining with other medications as drug concentrations may change due to interactions.

Serious side effects

Hives, severe swelling (edema), facial pallor, respiratory depression, shock, malignant hyperthermia (characterized by unexplained tachycardia, arrhythmia, blood pressure fluctuations, sudden temperature increases, muscle rigidity, dark red blood, cyanosis, hyperventilation, sweating, acidosis, hyperkalemia, myoglobinuria), central nervous system toxicity (tremors, seizures), anaphylaxis, hypotension, cardiac arrest

Mild side effects

• Drowsiness
• anxiety
• agitation
• negligence
• dizziness
• nausea
• vomiting
• delirium
• euphoria
• numbness

This medication should be stored in a sealed container to prevent contact with air and is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

The product is a colorless and transparent injectable solution in an ampule and vial.

Package unit

- Domestic Use: 5 mL × 20 ampules, 5 mL × 25 ampules, 20 mL × 10 vials - Export Use: 1.8 mL × 50, 100 ampules, 2 mL × 10 ampules, 5 mL × 10 ampules, 50 mL × 1, 10, 50, 100 vials, 5 mL × 10, 25 vials, 20 mL × 25 vials