Etravil 25 mg Tablet (Amitriptyline Hydrochloride)

Adult dose

○ Adults: Administer 30-75㎎ of amitriptyline hydrochloride per day orally in 2-3 divided doses, gradually increasing to 150㎎ per day if necessary. The dose may rarely be increased to 300㎎ per day. ○ For nocturnal enuresis, administer 10-30㎎ per day at bedtime. Adjust as appropriate according to age and symptoms.

This drug is an antidepressant used for the treatment of psychiatric disorders such as depression. It may increase the risk of suicidal thoughts or behaviors, particularly in young people aged 18 to 24, so caution is required when administering to this age group. All patients taking this medication should be closely monitored for suicidal tendencies or behavioral changes at the beginning of treatment and when the dosage is altered. Family members or guardians should also carefully observe the patient's condition and consult a doctor if necessary. Patients with certain conditions, such as heart disease, glaucoma, prostate enlargement, arrhythmias, or liver dysfunction should not use this medication or should use it cautiously. This medication may cause drowsiness or decreased concentration, so it is advisable to avoid driving cars or operating hazardous machinery while taking it. Additionally, this medication can interact with various drugs, so if the patient is taking other medicines, it is essential to inform the doctor or pharmacist. Women who are pregnant or breastfeeding should consult sufficiently regarding the necessity and risks of treatment, as the use of this medication may affect the fetus or infant. The safety and efficacy of this drug in children and adolescents have not been sufficiently established, and its use is not recommended, especially except in cases of enuresis. Elderly patients may be more sensitive to the side effects of this drug, so treatment should start with a lower dose and the patient's physical condition should be regularly monitored during administration.

Exercise paralysis, severe muscle rigidity, dysphagia, tachycardia, blood pressure changes, sweating, fever, leukocytosis, elevated serum CPK, decreased kidney function accompanied by myoglobinemia, high fever, altered consciousness, respiratory distress, circulatory collapse, dehydration symptoms, acute renal failure, hyponatremia, hypo-osmolarity, increased sodium excretion in urine, high urine output, seizures, altered consciousness, intestinal paralysis, loss of appetite, nausea, vomiting, constipation, abdominal distension and relaxation, intestinal content stagnation, myocardial infarction, stroke, syncope, hypotension, hypertension, tachycardia, bradycardia, palpitations, prolonged QT interval, arrhythmia, heart block, myocardial attack, abnormal ECG, allergic vasculitis, increased suicidal tendencies, coma, concentration disorders, disorientation, delusions, hallucinations, incoherence, mental confusion, agitation, anxiety, insomnia, nightmares, paralysis, tinnitus, sensory disturbances in limbs, peripheral neuropathy, ataxia, convulsive seizures, tremors, akathisia, headache, fatigue, drowsiness, dysarthria, EEG changes, restlessness, thirst, urinary difficulty, visual disturbance, ocular hypertension, sweating, frequent urination, mydriasis, unusual high fever, rash, urticaria, facial and sublingual edema, photosensitivity, agranulocytosis, leukopenia, purpura, thrombocytopenia, eosinophilia, nausea, vomiting, loss of appetite, diarrhea, taste disturbances, upper abdominal discomfort, stomatitis, swelling of the parotid gland, black tongue, swelling of the testicles, gynecomastia, breast enlargement, galactorrhea, decreased libido, increased libido, hypoglycemia, hyperglycemia, sexual dysfunction, hepatitis, jaundice, elevated ALT, elevated AST, fractures, drug reaction with eosinophilia and systemic symptoms (DRESS), dizziness, weakness, weight gain, weight loss, alopecia, involuntary movements around the mouth

This drug may be sensitive to light, so it should be stored in a light-resistant, tightly sealed container. Additionally, it is important to store it at room temperature, meaning not too hot or cold, to maintain its efficacy.

Appearance

Yellow round film-coated tablet

Package unit

1000 tablets/bottle