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Key information summary
Efficacy & effects
Treatment of respiratory infections such as acute and chronic bronchitis, pneumonia
Adult dosage
Adults and children over 12 years should take 2 tablets taken orally after meals, twice a day at 12-hour intervals. For long-term administration exceeding 14 days, the maintenance dose is 1 tablet taken twice a day, and for severe infections, the maximum dose is 3 tablets taken at a time.
Ingredients
Trimethoprim/Sulfamethoxazole
Rx / OTC
Prescription medication
Children's dosage
Children under 12 years of age should receive a divided dose of 6 mg of trimethoprim and 30 mg of sulfamethoxazole per kg of body weight, administered twice a day. For ages 6 to 11: 1 tablet once, twice a day. For ages 3 to 5: 1/2 tablet once, twice a day.
Appearance
White or almost white round tablets
Efficacy & effects
This antibiotic is effective against various bacteria and is used for respiratory diseases such as acute and chronic bronchitis, bronchiectasis, and pneumonia. It is also effective for upper respiratory infections such as sinusitis and otitis media. It can be utilized for urinary or genital infections such as acute and chronic cystitis, pyelonephritis, urethritis, prostatitis, and gonorrhea. Additionally, it is used to treat gastrointestinal bacterial infections such as typhoid, paratyphoid, and bacterial dysentery. This medication helps effectively improve various infection symptoms caused by multiple bacteria.
Dosage and Administration
Adults and children over 12 years should take 2 tablets taken orally after meals, twice a day at 12-hour intervals. For long-term administration exceeding 14 days, the maintenance dose is 1 tablet taken twice a day, and for severe infections, the maximum dose is 3 tablets taken at a time.
Precautions
This medication may cause severe skin adverse reactions, blood disorders, and serious respiratory hypersensitivity reactions, so if symptoms like skin rash, fever, or sore throat occur while using it, it should be discontinued immediately. Life-threatening immune reactions have been reported in patients taking this medication, and if such symptoms are suspected, the treatment should be stopped immediately and a physician consulted. It should not be used for pharyngitis caused by streptococci, especially in newborns, pregnant women, nursing mothers, certain patients with blood disorders, or patients with severely impaired liver or kidney function. Those with a history of blood disorders or those who are allergic, as well as patients with weak liver or kidney function, the elderly, and those with thyroid dysfunction should use this medication cautiously. Various blood abnormalities, skin rashes, liver dysfunction, kidney disorders, neurological symptoms, and gastrointestinal disturbances may occur, so any unusual symptoms should be reported to a doctor immediately. Regular tests like blood tests, liver function tests, and kidney function tests are crucial for early detection and management of adverse reactions. This medication has many drug interactions, which may exacerbate side effects depending on other medications taken, so it is essential to inform the doctor or pharmacist of any other medications being used. Women who are pregnant or may become pregnant and nursing mothers should not take this medication, and it should not be administered to newborns or infants under 2 months of age. The elderly may need dose adjustments and caution because renal function decline can prolong the drug retention in the body, leading to intensified side effects. In case of overdose, symptoms such as vomiting, diarrhea, headache, altered consciousness, and blood abnormalities may occur, hence it is vital to adhere strictly to the recommended doses and seek immediate medical attention in case of an overdose. This medication may cause inflammation or irritation at the injection site when administered intravenously, so caution is required, particularly when using injectable forms. If persistent diarrhea or abdominal pain occurs during antibiotic use, it may indicate serious intestinal diseases like pseudomembranous colitis, so immediate consultation with healthcare professionals is advised. If long-term use of this medication is necessary, it should be administered under regular clinical testing and physician supervision, and the treatment duration should be limited to the minimum necessary period.
Side effects
Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction High fever with severe rash, blisters, skin peeling, pain in mouth/eyes mucosa → severe skin adverse reactions Difficulty breathing or shortness of breath, asthma attacks, cough with fever and respiratory distress → respiratory issues Yellowing of the skin or eyes (jaundice), extreme fatigue throughout the body → liver abnormalities (jaundice) Sudden and
