Daehan 5% Glucose in Physiological Saline

Adult administration

Typically, adults receive an intravenous infusion of 500–1,000mL per day, divided into 2–3 doses. The administration rate is 250–500mL per hour (60–120 drops per minute), and in elderly patients, it should be 250mL per hour (60 drops per minute).

Child administration

For infants and young children, the administration rate should be 15–60mL per hour (4–15 drops per minute).

This medication is an intravenous solution containing glucose, which may increase the consumption of vitamin B1 upon administration, potentially leading to fatal vitamin B1 deficiency. This medication should not be used in patients with excessive fluid retention, hypertonic dehydration, or low potassium or high sodium levels in the blood. It should be administered with caution in patients with impaired kidney function, weak heart function, hypertonic dehydration, low urine output due to urinary obstruction, diabetes patients, patients with high blood chloride levels, and those with very low blood sodium levels. If this medication is administered in excessive amounts or too rapidly, it can cause edema in the brain or lungs, peripheral edema, acidosis, water intoxication, etc. Particularly, in newborns or premature infants, rapid administration can lead to water intoxication; thus, caution is required. There is also a risk of thrombosis at the intravenous injection site, so monitoring is necessary. During administration, blood glucose, electrolyte levels in the blood, and fluid balance should be checked regularly. During pregnancy, the risks to the fetus and treatment effectiveness must be carefully considered, and during labor, there is a risk of hyperglycemia and hypoglycemia for both the mother and newborn, requiring monitoring. Newborns, particularly premature or low-birth-weight infants, require meticulous management due to difficulties in blood sugar control, as hypoglycemia can cause severe brain damage. In infants and the elderly, caution should be exercised to avoid rapid or prolonged administration; in the elderly, especially those with weak heart and kidney function, care should be taken to avoid circulatory overload. In case of overdose, diuretics should be used to expel excessive fluid. Before administration, skin or equipment should be thoroughly disinfected to prevent infection, and it should be warmed to body temperature if stored cold before use. Once opened, it should be used immediately, and any leftover medication should not be used; during infusion, it should be administered slowly via intravenous injection. To prevent air embolism, care should be taken not to inject air from the container, and using multiple containers in series should be avoided.

Serious side effects

Peripheral edema, pulmonary edema

Mild side effects

• Cerebral edema
• pulmonary edema
• peripheral edema
• acidosis
• water intoxication
• thrombosis

This medication should be stored in a sealed container at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and safety.

Appearance

A colorless and transparent liquid with a slight salty and sweet taste, filled in a colorless and transparent glass or polypropylene, multilayer film plastic container.

Package unit

500mL/bottle, 500mL/bag, 1000mL/bottle, 1000mL/bag