Tetracycline Capsules 250 mg (Hydrochloride Tetracycline)

Key information summary

Efficacy & effects

This medication is effective against various bacteria and infections, including Rickettsia, Mycoplasma pneumonia, Chlamydia, Yersinia pestis, Brucella, and Treponema pallidum. It is primarily used for typhus, scrub typhus, Rocky Mountain spotted fever, Mycoplasma pneumonia, lymphogranuloma venereum, cholera, plague, brucellosis, syphilis, anthrax, acne, and several respiratory infections. It is also effective for respiratory infections such as tonsillitis, bronchitis, and pneumonia, as well as urogenital infections like gonorrhea, cystitis, and urethritis. This medication is used to treat various tissue infections, including abscesses, lymphangitis, osteomyelitis, and acute dacryocystitis. It is particularly helpful for inflammatory diseases such as otitis media, sinusitis, and mastitis. Overall, it is used for treating a wide range of bacterial infections, improving the patient's condition.

Dosage

As tetracycline hydrochloride, the dosage is 1 g (potency) per day, divided into 4 doses. It should not exceed the adult dosage. The medication should be continued for 24 to 48 hours after symptoms subside and fever abates. Food, oil, and dairy products can interfere with the absorption of this medication, so it should be administered 1 hour before or 2 hours after meals. For the prevention of rheumatic fever or the manifestation of glomerulonephritis, treatment should last at least 10 days.

Precautions

This medication should not be used in certain patients. Those with allergies to this drug, its components, or other antibiotics of the same class should not take it. Women who are pregnant or may become pregnant, nursing mothers, and children under 12 years old should avoid this medication due to risks of tooth discoloration and skeletal development issues. Patients with impaired kidney function or severe liver dysfunction should also refrain from using this medication. Additionally, those taking specific skin treatments known as retinoids should avoid using this medication together. Patients with lactose intolerance or certain genetic metabolic disorders should also avoid this medication. Patients with impaired kidney function should take this medication cautiously, reducing the dosage and frequently monitoring blood concentration. This medication may cause sensitivity to sunlight, so patients at risk for sun exposure should be careful as their skin may burn easily. Patients with liver or kidney issues or those taking hepatotoxic or nephrotoxic medications should also exercise caution. Those with esophageal problems should be careful as this medication may cause esophageal ulcers. Patients who find oral intake difficult, the elderly, or those with a generally poor health condition should be monitored for symptoms of vitamin deficiency. Patients with allergies or a history of asthma and urticaria should also be cautious of possible hypersensitivity reactions. This medication may produce various side effects, including hepatic dysfunction, gastrointestinal discomfort, skin rashes, renal dysfunction, and allergic reactions. Particularly rare side effects may include hepatitis, esophagitis, severe skin rashes, acute renal failure, and blood abnormalities; if such symptoms occur, discontinue the medication immediately and consult a physician. Long-term use may lead to symptoms like thyroid pigmentation or increased intracranial pressure, so caution is advised. It is recommended that this medication be used only for the minimum necessary period to prevent the development of resistant bacteria. During antibiotic use, infections may arise from the overgrowth of other organisms, such as Candida; therefore, continued monitoring is necessary. Patients receiving this medication for prolonged periods should regularly undergo tests for blood, kidney, and liver function. While taking this medication, headaches, dizziness, and vision disturbances may occur, making it advisable to avoid operating dangerous machinery. This medication may interact with other drugs; therefore, if you are taking any other medications, inform your doctor or pharmacist. Special caution is warranted when used in combination with anticoagulants, oral contraceptives, antacids, certain anticonvulsants, and immunosuppressants. Furthermore, taking this medication alongside specific photosensitive skin medications may increase the risk of skin reactions. Women who are pregnant or breastfeeding should avoid this medication, as it may affect the development of the fetal skeletal system and teeth, especially in the later stages of pregnancy. If breastfeeding, they should either discontinue breastfeeding or avoid taking this medication. Children, particularly those under 12 years old, should not take this medication due to the risk of tooth discoloration and skeletal development issues. Elderly patients may experience side effects more readily due to decreased physiological function, so they should start with a lower dosage and carefully monitor kidney, liver, and heart function. When taking this medication, it should be taken standing or sitting with plenty of water, ensuring it does not linger in the esophagus, and taking it just before bedtime should be avoided. In case of overdose, symptoms such as vomiting, liver and kidney damage, esophagitis, and severe allergic reactions may occur; immediate medical attention should be sought for appropriate treatment.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), profound general lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination.

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