Jeil Glucose Injection

Adult administration

Administer 20-500mL intravenously per dose. The intravenous infusion rate as dextrose should be less than 0.5g/kg per hour. Suitable amounts should be used for dissolving/diluting the injection. Adjust according to age and symptoms.

This drug may introduce glass fragments when cutting the glass container of the ampoule injection, so caution is advised especially when administering to children or the elderly. Patients receiving intravenous dextrose should be cautious as it may increase the consumption of vitamin B1 (thiamine), leading to severe deficiency. It should not be administered to patients with dehydration, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmotic coma, glucose intolerance, anuria, hepatic coma. Particularly, this medication in hypertonic form should not be administered to patients with spinal or intracranial hemorrhage and must be used with caution in severely dehydrated patients as it may exacerbate hyperosmotic conditions. In patients who are prone to potassium, phosphorus, or magnesium deficiency, those with hyponatremia, diabetes insipidus, renal failure, heart failure, severe malnutrition, thiamine deficiency, sepsis, severe or trauma patients, those in hemodilution, chronic uramia, and diabetic patients, it should be administered with caution. Rapid or large volume administration may cause electrolyte imbalances, so dosage and administration rate should be adjusted, and exceeding the recommended dosage may elevate blood bilirubin and lactate levels. This drug may cause side effects such as hypokalemia, hyperosmotic coma, acidosis, dehydration, hyperosmotic syndrome, polyuria, phlebitis, thrombosis, and pain at the injection site, requiring caution. With long-term use, it may affect insulin secretion requiring insulin to control blood glucose; thus, post-surgery or in patients with glucose intolerance, blood glucose levels should be monitored closely during administration. During pregnancy, the risks and therapeutic benefits to the fetus should be carefully considered, and during labor, maternal and neonatal blood glucose and metabolic states should be closely monitored. Children, especially neonates or low birth weight infants, may have immature fluid and electrolyte regulation abilities, necessitating frequent checking of blood electrolyte levels and close monitoring of blood glucose changes. Elderly patients may have a decline in physiological function, so care should be taken during administration. Overdosage may present with hyperglycemia or diabetic symptoms, potentially necessitating insulin administration. Subcutaneous injections can cause local irritation and circulatory failure and should be avoided. Unused solution after opening should be discarded immediately. Attention should be given to infection prevention during injection, especially in cold weather, where it is recommended to warm up to body temperature before administration. Sudden cessation after administering a concentrated solution may induce hypoglycemia, requiring a gradual taper. It should not be administered simultaneously with blood. When mixed with other medications, a thorough understanding of the potential interactions and side effects is essential, and it is safest to use immediately after mixing. Additionally, to avoid the risk of air embolism due to air remaining in the container, continuous connection of containers should be avoided.

• Electrolyte loss
• elevated bilirubin levels
• elevated lactate levels
• hypokalemia
• hyperosmolar coma
• acidosis
• dehydration
• hyperosmolarity
• polyuria
• fluid or solute overload

This medication should be stored in a sealed container to avoid contact with air, ideally kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the medication.

Appearance

A colorless, transparent liquid with a sweet taste contained in a colorless, transparent ampoule or plastic (polypropylene or polyethylene) aqueous injection container.

Package unit

20mL × 10 ampoules, 20mL × 50 plastic aqueous injection containers