Jeil Glucose Injection

Key information summary

Efficacy & effects

This medication is effective for providing energy needed in hyperkalemia, circulatory collapse, and hypoglycemia. It is also used together with cardiac therapy to improve heart function, as well as for fluid and energy replenishment. It can aid in the treatment of drug or poison overdose. Therefore, this medication is used for treating hyperkalemia, circulatory disorders, hypoglycemic states, and toxic overdose.

Dosage

Administer intravenously at a dose of 20-500mL. The intravenous infusion rate should be kept below 0.5g/kg per hour when administering dextrose. Use an appropriate amount for dissolving or diluting the injectable solution. Adjust according to age and symptoms.

Precautions

Care must be taken when using this medication, especially when administering to children or the elderly, as glass fragments can be introduced when breaking the glass container of the ampoule. Patients receiving intravenous dextrose should be careful, as it can increase the consumption of vitamin B1 (thiamine), potentially leading to severe deficiency. This medication should not be administered to patients with dehydration due to storage, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucose intolerance, anuria, or hepatic coma. Particularly, the hypertonic form of this medication should not be administered to patients with spinal hemorrhage, intracranial hemorrhage, or tremulous delirium, and caution should be observed in severely dehydrated patients as it could exacerbate hyperosmolar states. It should be administered with caution to patients who are prone to deficiencies in potassium, phosphate, magnesium, or those with hyponatremia, diabetes insipidus, renal failure, heart failure, severe malnutrition, thiamine deficiency, sepsis, severe or trauma cases, blood dilution, chronic uremia, and diabetes mellitus. Rapid or excessive administration may cause electrolyte imbalances, so dosage and administration speed should be controlled, and exceeding the recommended dosage may increase blood bilirubin and lactate levels. This medication may cause side effects such as hypokalemia, hyperosmolar coma, acidosis, dehydration, hyperosmolarity, polyuria, phlebitis, thrombosis, and injection site pain, requiring careful monitoring. Prolonged administration may affect insulin secretion, necessitating insulin co-administration for blood glucose control, and careful monitoring of blood glucose levels should be done in postoperative or glucose intolerant patients. When used during pregnancy, the risks to the fetus and the therapeutic benefits must be carefully considered, and during labor, the blood glucose and metabolic state of both the mother and newborn must be closely monitored. In children, especially newborns or low-birth-weight infants, fluid and electrolyte regulation abilities may be immature, thus frequent checks of blood electrolyte levels and close monitoring of blood glucose changes are necessary. Elderly patients may have diminished physiological functions, so administration should be executed with extra caution. Overdosage may lead to hyperglycemia or symptoms of diabetes, necessitating insulin administration. Subcutaneous injections should be avoided as they may cause local irritation and circulatory failure, and any unused portion of the opened solution must be discarded immediately. Care should be taken to prevent infections during injection, particularly in cold seasons, where it is advisable to warm the solution to body temperature before administration. A sudden stop in the administration of high-concentration solutions can lead to hypoglycemia, requiring gradual discontinuation, and it should not be administered simultaneously with blood products. When mixed with other medications, the potential for interactions and the possibility of side effects must be thoroughly understood, and it is safest to use immediately after mixing. Additionally, to prevent the risk of air embolism due to air remaining in the container, continuous connection of containers should be avoided.

Side effects

Hypokalemia, acidosis, dehydration, hyperosmolarity, polyuria, fluid and electrolyte imbalance, congestion, pulmonary edema, hyperglycemia, renal impairment, fever, phlebitis, thrombosis, blood leakage, injection site pain, uremia, elevated bilirubin and lactate levels, serum electrolyte abnormalities, changes in blood glucose concentration, hypoglycemia, insulin production changes, agglutination reactions, thrombophlebitis, local irritation, infection risk, risk of air embolism

Alternatives / Same-ingredient medications

• Jungwoo 5% Glucose Injection

  Same ingredient
• Jungwoo 20% Glucose Injection

  Same ingredient
• Jungwoo 50% Glucose Injection

  Same ingredient
• Daehan Glucose Injection (10%)

  Same ingredient

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