Is there any way to get rid of the wrinkles on my wrists?

As I bent my wrist like this,

You have deep wrinkles.

So these days, even when I apply hand cream

I made a point to apply it thoroughly to this part as well.

I'm trying to be careful not to fold it like this if possible.

But it's already formed deeply...

I became curious if it is also possible to treat wrinkles on the wrist.