Empagagliptin 2L-Proline/Metformin Tablets 5/1000 mg

Adult dose

The recommended dose for this medication is 1 tablet once daily, taken twice a day. The maximum recommended daily dose for empagagliptin is 25 mg, and for metformin, it should not exceed 2000 mg. For patients on monotherapy with metformin or combined with other medications, empagagliptin can be taken at 5 mg twice a day (total daily dose of 10 mg), and can be increased to a total of 25 mg daily if tolerance is good and additional blood sugar control is needed.

This medication is helpful in controlling blood sugar. However, it may cause a dangerous condition known as severe lactic acidosis, so caution is needed. When used with other diabetes medications, hypoglycemia may occur, so it should be used carefully. Patients with significantly impaired kidney function, acute infections, dehydration, or cardiac issues should not use this medication. Also, it is safe for pregnant or breastfeeding women to avoid this medication. Kidney function should be monitored regularly during treatment, and special caution should be taken if symptoms of dehydration or gastrointestinal discomfort occur. Urinary tract infections or genital infections may occur, so any symptoms should be reported to healthcare providers immediately. If sudden fatigue, muscle pain, difficulty breathing, or abdominal pain occurs while taking this medication, it could be a sign of lactic acidosis and immediate medical attention should be sought. It may be necessary to consult with a doctor about temporarily stopping the medication before surgery or radiological examinations. Taking this medication with alcohol can be dangerous, so it is best to avoid drinking. Elderly or patients with weak kidney function may require dose adjustments and regular monitoring. There is a risk of hypoglycemia, so caution should be exercised in skipping meals or after vigorous exercise. Monitoring vitamin B12 levels during the medication period is advisable. Following these precautions can ensure safe therapeutic effects.

Serious side effects

Hives, angioedema, necrotizing fasciitis of the perineum, lactic acidosis, ketoacidosis, urosepsis, pyelonephritis, severe edema, liver dysfunction (jaundice), severe allergic reactions, severe skin adverse reactions, difficulty breathing, asthma attacks, heart problems (myocardial infarction, angina), cerebral infarction, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, potential worsening of diseases due to increased urine output, severe edema or urination.

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air and light, so it should be stored in a sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. By storing it this way, the effects of the medication can be safely maintained.

Appearance

Dark yellow oval film-coated tablets

Package unit

30 tablets/bottle, 60 tablets/bottle