Lotodipine Tablets 5/5 mg (Rosuvastatin, Amlodipine)

Adult dose

This medication is administered exclusively to adults, and the dosage should be individualized based on the efficacy and tolerability of amlodipine and rosuvastatin for each patient. ○ Amlodipine Adults: Amlodipine is taken orally once daily at 5 mg and may be increased to a maximum of 10 mg daily based on the patient's response. Adjust as appropriate according to symptoms. ○ Rosuvastatin The initial dose is 5 mg once daily, and for more significant LDL-cholesterol reduction needs, the maintenance dose can be adjusted accordingly.

This medication should not be used in patients who are allergic to certain ingredients or have shown hypersensitivity reactions. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication unless the likelihood of pregnancy is low and there is a full awareness of the risks to the fetus. Patients with severely impaired liver function or active liver disease, severe aortic stenosis, those in shock, muscle disorders, and those taking certain immunosuppressants should also avoid this medication. Patients with severe renal impairment should not use this drugs, and those at high risk for muscle disorders should be especially cautious. Patients with hypertension or renal failure, elderly patients, and those with myasthenia gravis should be closely monitored when using this medication, and regular liver function tests and muscle-related tests are recommended. If symptoms such as myalgia, muscle weakness, or cramps occur, patients should inform their healthcare provider immediately, and discontinuation of the medication may be necessary. This medication may affect the liver or kidneys, so regular testing is required, and rare but serious liver damage or severe muscle-related side effects may occur. Additionally, interactions may arise when used with other medications, so current medications must be disclosed to the doctor or pharmacist. Pregnant or nursing women should not take this medication and women capable of becoming pregnant should use appropriate contraception. Safety in children is not established, hence it is not administered to pediatric patients. In cases of overdose, severe hypotension or cardiac symptoms may occur, necessitating immediate emergency treatment, and this medication should be kept out of reach of children.

Serious side effects

Urticaria, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms, severe edema, jaundice, hepatitis, abnormal liver function tests, severe muscle weakness, ophthalmoplegia, myopathy, rhabdomyolysis, acute renal failure, thrombocytopenia, oliguria, severe allergic reactions, severe skin reactions, respiratory issues, liver abnormalities (jaundice), severe neurological symptoms, severe edema, or urinary abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• myalgia
• muscle cramps
• weakness
• fatigue
• numbness

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. Additionally, it is best to keep the medication at room temperature, not exceeding 30°C or falling below 1°C.

Appearance

Orange round film-coated tablet

Package unit

30 tablets/bottle