Atorvastatin and Ezetimibe Tablets 10/5 mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, it is administered in a dosage range of 10/5mg to 10/80mg daily. An initial dose of 10/5mg, 10/10mg, or 10/20mg is recommended. For patients who require greater reduction of LDL-cholesterol, an initial dose of 10/40mg is recommended. After starting treatment or adjusting the dose, check blood lipid levels at intervals of more than 2 weeks.

This medication may pose a risk of serious muscle problems; therefore, if muscle pain or weakness suddenly appears, immediate consultation with a physician is necessary. Do not use this medication if you have impaired liver function or liver disease, and regular liver function tests must be conducted. Women who are pregnant, potentially pregnant, or breastfeeding should not take this medication. Patients who consume excessive alcohol or have a history of liver disease should use this medication with caution, as well as those prone to myopathy. Interactions may occur when taken with other medications, so it is essential to inform the prescribing physician or pharmacist of any other medications being taken. Some side effects such as dyspepsia, abdominal pain, diarrhea, headache, dizziness, myalgia, back pain, muscle cramps, eye pruritus, giant papillary conjunctivitis, keratitis, capsule opacity, blurred vision, COVID-19, nasopharyngitis, upper respiratory tract infections, chest pain, acne, uterine leiomyoma, skin abrasions, and ulnar fractures may appear in some patients; if unusual symptoms persist, consult healthcare professionals. Particularly elderly patients or those with impaired kidney function may experience muscle-related symptoms more frequently, necessitating increased caution. During treatment, it is crucial to regularly conduct blood tests and liver function tests to monitor health status. Additionally, it is important to maintain an appropriate diet and make lifestyle improvements while taking this medication, and if sudden muscle pain or weakness occurs, treatment should be halted and a physician should be consulted.

Serious side effects

• Hives
• severe swelling (edema)
• chest discomfort
• increased blood creatine phosphokinase
• headache
• visual disturbances
• hematuria
• generalized edema
• liver abnormalities (jaundice)
• hepatitis

Mild side effects

• Dry mouth
• increased blood creatine phosphokinase
• cough
• oropharyngeal pain
• abdominal discomfort
• diarrhea
• dyspepsia
• nausea
• dizziness
• paresthesia

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/bottle