Sitapluse Sustained Release Tablet 50/1000 mg (Sitagliptin, Metformin)

Adult dose

For the 100/1000 mg sustained-release tablet, take 1 tablet once daily. Patients taking 50/500 mg sustained-release tablets or 50/1000 mg sustained-release tablets should take 2 tablets simultaneously once daily. 1. For patients not currently treated with metformin: The initial dose is a total daily amount of sitagliptin 100 mg and metformin 1000 mg. If adequate blood sugar control is not achieved,

This medication is a diabetes treatment that contains sitagliptin and metformin, aiding in blood sugar control. Caution should be exercised for allergic reactions while taking this medication. Rarely, anaphylaxis, angioedema, and serious skin conditions may occur, so if symptoms such as skin rash or difficulty breathing arise, stop taking the medication immediately and consult a physician. Also, this medication may potentially cause pancreatitis, so if symptoms of pancreatitis such as abdominal pain, vomiting, or loss of appetite occur after taking, inform your healthcare provider immediately. The metformin component can lead to a dangerous condition known as lactic acidosis in severe cases; hence, patients with renal dysfunction or certain diseases such as dehydration, severe infection, or heart failure should not take it. Particularly, patients with moderate to severe renal impairment, those with acute heart failure, and those undergoing tests with iodinated contrast media should avoid using this medication, as should pregnant or breastfeeding women. Attention is required as irregular meal patterns, excessive exercise, or taking certain medications may increase the risk of lactic acidosis or hypoglycemia. This medication contains tartrazine (Yellow No. 4) dye, so it should be taken cautiously by those who are allergic to this component. During treatment, gastrointestinal disturbances such as nausea, diarrhea, or abdominal pain may occur, and in rare cases, hypoglycemia or skin rashes may arise. Before taking the medication, it is essential to consult with a doctor or pharmacist to ensure it is appropriate for your health condition, and any unusual symptoms should be discussed with a specialist immediately.

Serious side effects

Urticaria, severe allergic reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome), acute pancreatitis, severe lactic acidosis, hypoglycemia

Mild side effects

• Gastrointestinal adverse reactions
• hypoglycemia
• lactic acidosis
• coma
• metabolic acidosis
• inadequate food intake
• vigorous physical activity
• etc.

This medication is sensitive to air and moisture, so it should be stored in a sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. Proper storage can help preserve the efficacy and safety of the medication for an extended period.

Appearance

Bright green oval sustained-release film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle