Tosjet A Tablets 10/40/10 mg (Ezetimibe, Atorvastatin Calcium Trihydrate, Amlodipine Besylate)

Adult dose

The recommended dosage for this medication is one tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). This medication should be swallowed whole and not chewed, divided, or crushed. For Amlodipine, administer 5 mg orally once daily, with the maximum dose of 10 mg adjusted according to the patient's response. The Ezetimibe/Atorvastatin combination can be taken regardless of meals.

This medication carries a risk of muscle problems; thus, if severe muscle pain or weakness occurs, it is essential to consult a doctor immediately. Patients with poor liver function or a history of liver disease must undergo liver function tests before taking this medication and should discontinue use if liver function abnormalities occur. This medication may increase the risk of side effects when taken with specific drugs; therefore, it is crucial to inform your doctor or pharmacist if you are taking any other medications. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication; fertile women are advised to use appropriate contraception while on this medication. Patients with a history of hypertension, liver disease, kidney disease, or muscle diseases, as well as elderly patients, should be particularly cautious when taking this medication, and regular check-ups may be necessary. Although rare, this medication can cause allergic reactions such as skin rashes, hives, and difficulty breathing. If such symptoms occur, immediate treatment is necessary. Dizziness or drowsiness may occur when driving or operating machinery; caution is advised if such symptoms are present. Regular blood tests and liver function tests during the use of this medication are essential to monitor for potential side effects.

Serious side effects

Hives, angioedema, toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, jaundice, hepatitis, liver failure, myopathy, rhabdomyolysis, myositis, acute kidney failure, thrombocytopenia, anaphylaxis, severe edema, chest tightness, difficult breathing, asthma attacks, severe allergic reactions, severe neurological symptoms (headache, confusion, seizures, etc.), kidney failure, severe edema accompanied by increased blood pressure.

Mild side effects

• Headache
• constipation
• indigestion
• fatigue
• muscle pain
• joint pain
• dizziness
• nausea
• diarrhea
• vomiting

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help preserve the effectiveness of the drug.

Appearance

White, rectangular, film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]