Janustine Met XR Controlled Release Tablet 50/1000 mg

Adult dose

For this medication 100/1000 mg controlled-release tablet, take once daily, one tablet per dose. Patients taking this medication 50/500 mg controlled-release or 50/1000 mg controlled-release tablet take twice daily, two tablets at the same time. 1. For patients not currently treated with metformin: Starting dose is a total daily amount of 100 mg of sitagliptin and 1000 mg of metformin. Gradually increase metformin's

This medication is an antidiabetic treatment containing both sitagliptin and metformin. Firstly, severe allergic reactions may occur while taking this medication; if symptoms such as skin rash, itching, or difficulty breathing arise, you should immediately discontinue use and consult a physician. Serious side effects including acute pancreatitis, which is inflammation of the pancreas, have been reported while taking this medication. If abdominal pain, vomiting, or severe indigestion occurs, you must visit a hospital immediately. Additionally, metformin may rarely cause a life-threatening condition known as lactic acidosis. If symptoms such as severe fatigue, muscle pain, breathing difficulty, abdominal pain, or changes in consciousness appear, you should immediately stop taking the medication and inform healthcare professionals. This medication should not be used in patients with severely impaired kidney function, severe infections, dehydration, heart failure, or acute myocardial infarction. It should also be discontinued for a certain period before and after surgery. During treatment, it is important to regularly monitor kidney function, blood tests, and vitamin B12 levels. This medication may cause hypoglycemia, so patients should be vigilant for signs of low blood sugar if meals are missed or irregular, if intense exercise is performed, or if taken with other blood sugar-lowering agents. Women who are pregnant or may become pregnant, as well as women who are breastfeeding, should not take this medication. This medication's safety and efficacy have not been established in children, and caution is necessary for elderly patients due to decreased kidney function. Finally, avoid excessive alcohol consumption while taking this medication and consult your physician or pharmacist about potential interactions when taking other medications.

Serious side effects

Hives, angioedema, anaphylaxis, Stevens-Johnson syndrome, severe skin reactions, acute pancreatitis, acute renal failure, severe and debilitating joint pain, blistering dermatitis, liver abnormalities (elevated liver enzymes, possibility of jaundice), severe lactic acidosis, hypoglycemia (especially severe hypoglycemia), acute renal failure, severe edema or urinary abnormalities

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• muscle pain
• limb pain

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. The appropriate storage temperature is room temperature between 1 and 30 degrees Celsius, and it is important to keep it away from direct sunlight and damp places.

Appearance

Bright green oval-shaped controlled-release film-coated tablets

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle