Esporg Duo Sustained Release Tablet 10/1000 Milligrams

Adult dose

This medication is generally administered once daily along with the evening meal. The maximum dosage is 10 mg dapagliflozin and 2000 mg sustained-release metformin once daily, administered as 2 tablets of 5 mg/1000 mg. For patients with no prior experience of diabetes medication, the initial dosage as the first-line therapy is one tablet of 5 mg/500 mg or 10 mg/500 mg once daily to achieve adequate blood sugar control. To reduce gastrointestinal side effects of metformin, gradual titration of the dosage is recommended.

This medication can cause a rare complication called severe lactic acidosis, so it should not be used by patients with impaired kidney function, serious infections, dehydration, or cardiovascular issues. Care should be taken as there is a risk of hypoglycemia when this medication is used with insulin or sulfonylurea diabetes drugs. Patients with decreased kidney function or low fluid volume should consult a physician before using this medication and carefully check kidney function and fluid status. Pregnant or breastfeeding women should not take this medication, and should cease administration immediately if pregnancy is confirmed. This medication may increase the risk of genital infections or urinary tract infections, and timely treatment should be sought if any infection symptoms appear. Dehydration or low blood pressure symptoms due to reduced fluid volume may occur; if dizziness or blood pressure drops are noted, inform a doctor. Vitamin B12 deficiency may occur, so it is advisable to periodically check blood vitamin B12 levels during long-term use. Excessive alcohol consumption should be avoided while taking this medication, and if surgery or imaging tests are scheduled, it may be necessary to suspend the medication for a certain period before and after. Elderly patients or those with decreased kidney function should have their medication dosage adjusted and kidney function monitored frequently. This medication can cause hypoglycemia, so when used in combination with blood sugar-lowering agents, attention should be paid to hypoglycemic symptoms, and doses may need adjusting accordingly. In the case of overdose, seek medical attention immediately, as side effects such as dizziness may be present, necessitating caution when driving or operating machinery. Store this medication out of the reach of children, and keep in its original container.

Serious side effects

• Guillain-Barré syndrome
• bacterial pneumonia
• sialadenitis
• chest pain
• thermal burn
• wrist fracture
• gastrointestinal stromal tumors
• malignant neoplasm of the lung
• uterine fibroids
• atrial fibrillation

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary tract infections
• hypoglycemia
• reduced fluid volume
• thirst
• dizziness
• constipation
• dry mouth
• low back pain

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is safe to store at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance

Yellow, elliptical, convex, sustained-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP*5)], 30 tablets/bottle