Exmetrex XR Tablet 50/1000 mg

Adult dose

The 100/1000 mg sustained-release tablet is to be taken once daily, one tablet at a time. Patients taking the 50/500 mg sustained-release tablet or 50/1000 mg sustained-release tablet should take it once daily, two tablets at a time. 1. For patients who are not currently being treated with Metformin: The initial dosage of this medication is 100 mg of sitagliptin and 1000 mg of metformin as a total daily dose. Initial dosage of

This medication consists of sitagliptin and metformin and is used for diabetes treatment. First, sitagliptin can rarely cause severe allergic reactions, so if symptoms like hives, rash, or difficulty breathing occur, discontinue use immediately and consult a physician. Additionally, sitagliptin may lead to a serious side effect called pancreatitis, which involves inflammation of the pancreas; if symptoms like abdominal pain, vomiting, or nausea persist, notify healthcare professionals immediately. The metformin ingredient can cause lactic acidosis, a rare but potentially fatal metabolic disorder; if sudden muscle pain, difficulty breathing, fatigue, abdominal pain, or weakness occurs, stop taking the medication immediately and visit a hospital. This medication should not be administered to patients with impaired kidney function, severe infections, dehydration, heart failure, or acute myocardial infarction, and it should be suspended for a certain period before and after imaging tests using iodinated contrast agents. It is advisable for pregnant or nursing women and children under 18 years of age not to use this medication. While taking this medication, regular checks of kidney function, blood tests, and vitamin B12 levels are necessary, and excessive alcohol consumption should be avoided. Also, irregular meals, excessive exercise, or combining with other hypoglycemic agents can increase the risk of hypoglycemia, so caution is required. If surgery is planned, medication should be stopped 48 hours prior to the procedure and resumed only after normal kidney function is confirmed post-surgery. During the course of taking this medication, gastrointestinal disorders, headaches, and upper respiratory infections may occur; if symptoms are severe, consult a physician. Finally, while this medication assists with blood sugar control, it is essential to adhere to dietary and exercise protocols, along with regularly monitoring blood sugar and kidney function for safe treatment.

Serious side effects

Hives, anaphylaxis, angioedema, rash, exfoliative skin disorders (including Stevens-Johnson syndrome), acute pancreatitis (including hemorrhagic or necrotizing), acute renal failure, severe and disabling arthralgia, bullous pemphigoid, severe lactic acidosis, hypoglycemia (including severe), elevated liver enzymes, severe allergic reactions, severe skin adverse reactions, respiratory issues, liver abnormalities (jaundice), severe neurological symptoms, severe edema

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air or moisture ingress, ideally at room temperature between 1°C and 30°C. By doing so, the effectiveness of the medication can be maintained for a longer period.

Appearance

Bright green, oval-shaped, biconvex, sustained-release film-coated tablet

Package unit

28 tablets/bottle, 56 tablets/bottle, 200 tablets/bottle