Sitagliptin Metformin Tablets 50/500 mg

Adult dose

This medication is generally taken twice a day with food, and the dosage should be gradually increased to reduce gastrointestinal adverse effects associated with Metformin. The initial dosage is determined based on the patient's current treatment regimen. 1. Patients not currently treated with Metformin: Take this medication 50/500 mg, 1 tablet twice a day. The dosage can be increased to 50/1000 mg, 1 tablet twice a day.

This medication contains Sitagliptin and Metformin, and is used in the treatment of diabetes. Severe hypersensitivity reactions may occur while taking this medication, so if symptoms such as rash, hives, or difficulty breathing arise, discontinue use immediately and consult a physician. Acute pancreatitis has been reported, so if abdominal pain, vomiting, or severe abdominal discomfort occur, inform healthcare professionals immediately. This medication should not be used in cases of severe renal impairment or conditions that may affect kidney function such as acute heart failure, acute myocardial infarction, or severe infection. Before and after examinations using iodinated contrast agents, the administration of this medication should be discontinued, and it can only be resumed once normal kidney function is confirmed. It is safer not to take this medication during pregnancy or if pregnancy is possible, and it is not recommended for nursing mothers. Elderly patients are at a higher risk for decreased renal function, so kidney function should be regularly monitored and dosage adjusted accordingly. This medication can cause a rare but serious side effect called lactic acidosis, so if symptoms like sudden muscle pain, weakness, difficulty breathing, or abdominal pain occur, inform your doctor immediately. There is also a risk of hypoglycemia, especially when used in conjunction with insulin or sulfonylureas, so blood sugar levels should be carefully monitored. Alcohol may increase the risk of side effects from this medication, so excessive drinking should be avoided while taking it. Medication should be discontinued for a period before and after surgery, and it can be resumed only after the patient's condition stabilizes and kidney function is verified as normal. Regular blood tests and kidney function tests should be conducted while taking this medication, and periodic monitoring of vitamin B12 levels is recommended. Lastly, if any new symptoms or adverse reactions arise during treatment with this medication, consult healthcare professionals immediately.

Serious side effects

• Hives
• angioedema
• anaphylaxis
• rash
• Stevens-Johnson syndrome
• exfoliative dermatitis
• thrombocytopenia
• acute pancreatitis
• acute renal failure
• difficulty breathing

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• weakness
• pruritus

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Bright pink oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP x 3)]