Danggijanucombi Tablet 50/1000 mg

Adult dose

For antidiabetic therapy, this medication should be determined based on each patient's current treatment regimen, efficacy, and tolerability, without exceeding the maximum recommended daily dose of sitagliptin 100 mg and metformin 2000 mg. Generally, it is taken twice daily with food, and the dosage should be gradually increased to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients not treated with metformin: Initial dose

This medication is a diabetes treatment that contains both sitagliptin and metformin. First, this drug can cause rare but serious allergic reactions, so if symptoms such as skin rash, hives, or difficulty breathing occur, stop taking it immediately and consult a physician. Moreover, there may be an inflammation of the pancreas known as pancreatitis, so if symptoms such as abdominal pain, nausea, or vomiting arise, you must seek medical attention right away. This drug should not be administered to patients with compromised kidney function, acute heart failure, myocardial infarction, or severe infections. Especially in cases of decreased kidney function, the ingredients of this drug can accumulate in the body, potentially leading to a dangerous condition known as lactic acidosis, so regular kidney function tests should be performed, and the medication should be discontinued if necessary. Lactic acidosis can present with symptoms such as muscle pain, weakness, difficulty breathing, and abdominal pain, so if these symptoms occur, you must immediately inform medical personnel. Avoid excessive alcohol consumption while taking this medication, and temporarily stop the medication during surgery, severe dehydration, or infection. Also, symptoms of hypoglycemia may occur, so do not skip meals, take the medication regularly, and exercise caution as the risk of hypoglycemia may increase when used in conjunction with other blood glucose-lowering agents. It is advisable for pregnant or breastfeeding women not to use this drug, and safety has not been established for children and adolescents under 18 years old. Finally, while taking this medication, regular kidney function and blood tests should be conducted to check for abnormalities, and if any unusual symptoms arise during treatment, consult a doctor immediately.

Serious side effects

Hives, severe hypersensitivity reactions (including anaphylaxis, angioedema, Stevens-Johnson syndrome, including exfoliative skin diseases), acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis), lactic acidosis, difficulty breathing, acute kidney failure, severe hypoglycemia, severe joint pain related to disability, bullous pemphigoid, liver abnormalities (including elevated liver enzymes), thrombocytopenia, severe edema, unstable angina, acute kidney failure, severe

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• weakness

This medication should be stored in a tightly sealed container to avoid exposure to air and preferably kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent deterioration.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP x 3)]