Nexiomeduo Tablet 20/800 mg

Adult dose

This medication should be taken on an empty stomach at least 1 hour before meals. It should be swallowed whole with at least half a cup of water. It should not be taken with any drinks other than water. It should not be chewed or crushed. - Treatment of erosive esophagitis: 40/800 mg once daily for 4 weeks - If not treated or symptoms persist, continue for another 4 weeks - Maintenance therapy to prevent recurrence: 20 mg once daily

This medication should not be administered to certain patients. For example, patients with allergies to this medication or its components, those who have experienced hypersensitivity reactions, patients taking certain antiviral agents, nursing women, and individuals with heart-related diseases or a history of myocardial infarction should not take this medication. Patients with liver or kidney dysfunction, elderly individuals, those with severe gastrointestinal ulcers, patients with compromised heart or lung functions, patients with electrolyte imbalances, and those who need to restrict sodium intake should use this medication carefully. Various adverse reactions may occur when taking this medication. For instance, headache, dizziness, indigestion, abdominal pain, skin rash, muscle pain, blood abnormalities, liver function abnormalities, and psychological changes have been reported. Additionally, serious skin reactions or muscle-related diseases may occur rarely, so immediate consultation with a physician is advised if symptoms appear. Since this medication inhibits gastric acid secretion, prolonged use may slightly increase the risk of infection due to bacterial growth in the stomach. Therefore, if symptoms like diarrhea persist, medical attention should be sought. Long-term high-dose use may increase the risk of fractures, so patients at risk for osteoporosis should undergo regular examinations. This medication may interact with certain drugs, so if taking other medications, it is essential to inform healthcare providers, particularly when using anticoagulants, anticonvulsants, antidepressants, and antiviral agents. The safety of this medication during pregnancy is not fully established; thus, it should be used cautiously under medical advice. It is advised not to use this medication while breastfeeding. In case of overdose, there is no specific antidote, so appropriate treatment should be provided according to symptoms, and it should be kept out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), jaundice, liver failure, encephalopathy, severe edema, increased blood pressure, sudden and very severe headache, seizures, altered consciousness, visual disturbances, paralysis, markedly reduced urine output, increased blood pressure

Mild side effects

• Leukopenia
• thrombocytopenia
• fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety
• mental confusion
• depression

This medication can be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain the storage temperature between 1 to 30 degrees Celsius to preserve the medication's efficacy and safety for an extended period.

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/bottle