Medication info

Poshuvet Duo Sustained Release Tablet 5/1000 mg

Prescription medicationTablet경구
Ingredient · strength
Dapagliflozin citric acid›7.35mg / 1 tabletMetformin Hydrochloride›1000mg / 1 tablet
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
A pink, double convex, egg-shaped film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202107130 · Approved 2021.10.26

Summary

Main use
Blood sugar control in type 2 diabetes and prevention of cardiovascular events
Who takes it
Adults
Adult dose
The dosage of this medication should be individualized based on the patient's current treatment, efficacy, and tolerance, without exceeding the maximum recommended dosage of dapagliflozin 10 mg and extended-release metformin 2000 mg. This medication is generally administered once a day with the evening meal. The maximum dosage of this medication is 10 mg of dapagliflozin/2000 mg of extended-release metformin, and it is typically administered as 2 tablets of 5 mg/1000 mg.

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

Blood sugar control in type 2 diabetes and prevention of cardiovascular events

  • Type 2 diabetes
  • abnormal blood sugar control
  • cardiovascular disease
  • cardiovascular risk factors
View approved original text

This medication is administered in conjunction with dietary and exercise therapy to help control blood sugar in adult patients with type 2 diabetes using dapagliflozin and metformin together. It is particularly suitable for patients with insufficient blood sugar control who have cardiovascular disease or risk factors. Please ensure to refer to the precautions regarding the occurrence of cardiovascular events upon administration. This medication effectively regulates blood sugar and improves the patient's health management.

How to take

Adult dose

The dosage of this medication should be individualized based on the patient's current treatment, efficacy, and tolerance, without exceeding the maximum recommended dosage of dapagliflozin 10 mg and extended-release metformin 2000 mg. This medication is generally administered once a day with the evening meal. The maximum dosage of this medication is 10 mg of dapagliflozin/2000 mg of extended-release metformin, and it is typically administered as 2 tablets of 5 mg/1000 mg.

Precautions

This medication is used for the treatment of diabetes and helps with blood sugar control. It may rarely cause a serious condition known as lactic acidosis, which can result in dangerous situations due to excessive accumulation of lactic acid in the body, thus caution is necessary. When taken with other diabetes medications, hypoglycemia may occur, so attention to symptoms is required. Patients with poor kidney function, dehydration, severe infections, heart issues, or liver dysfunction should not use this medication. Patients who are about to undergo surgery or are scheduled to use radiological contrast agents should temporarily discontinue this medication and should restart it only after confirming normal kidney function. Women who are pregnant or breastfeeding should refrain from using this medication for safety. Elderly patients or those with compromised kidney function should regularly monitor their kidney function before and after taking this medication and should be cautious for symptoms of hypotension or fluid deficiency. This medication may increase the risk of genital infections or urinary tract infections, so if related symptoms arise, immediate consultation with healthcare professionals is necessary. Vitamin B12 deficiency may occur; therefore, it is advisable to periodically check vitamin B12 levels during prolonged use. Excessive alcohol consumption should be avoided, and during the use of this medication, any interactions with other drugs that may affect blood sugar control should be discussed with a physician. During the use of this medication, dizziness or symptoms of hypoglycemia may occur, so caution is required when driving or operating machinery. Keep out of the reach of children and store in the original container to maintain the quality of the medication.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, shortness of breath, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, coughing + respiratory abnormalities accompanied by fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Hypoglycemia
  • dizziness
  • constipation
  • dry mouth
  • back pain
  • dysuria
  • polyuria
  • nocturia
  • pruritus of the vulva
  • pruritus of the genital area
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  • increased hematocrit
  • dyslipidemia
  • increased serum creatinine
  • increased blood urea
  • weight loss
  • diarrhea
  • nausea/vomiting
  • decreased/deficiency of vitamin B12
  • upper abdominal pain
  • indigestion
  • abdominal discomfort
  • abdominal pain
  • gastric ulcer
  • irritable bowel syndrome
  • toothache
  • headache
  • facial paralysis
  • peripheral neuropathy
  • sensory disturbances
  • drowsiness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture. It is recommended to maintain a storage temperature between 1 degrees Celsius and 30 degrees Celsius.

Appearance and packaging

Appearance

A pink, double convex, egg-shaped film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.