Esomeprazole Duo Tablet 20/800 mg

Adult dose

This medication should be taken at least 1 hour before meals on an empty stomach. Swallow it whole with at least half a cup of water. Do not take with any beverage other than water. Do not chew or crush it. 1. Adults - Treatment of erosive gastroesophageal reflux disease: Administer 40/800 mg once daily for 4 weeks. In case the esophagitis is untreated or symptoms persist, take for an additional 4 weeks. - Maintenance therapy for preventing recurrence in patients with esophagitis: 20/800 mg once daily. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis · 20/800 mg once daily. If symptoms are not controlled after 4 weeks, further consultation is required. · Once symptoms are relieved, for subsequent symptoms, administer 20/800 mg once daily. · In adults, 20/800 mg may be provided once daily as needed. In patients with increased risk of gastric and duodenal ulcers due to non-steroidal anti-inflammatory drug therapy, it is not recommended to administer it as needed for subsequent symptom control. 2. In cases of liver dysfunction: No dose adjustment is necessary for patients with mild to moderate liver impairment. For patients with severe liver impairment, the dose of this medication must not exceed 20/800 mg.

This medication should not be administered to certain patients. For example, patients who are allergic to this drug or its ingredients, those taking certain antiviral medications, breastfeeding women, and patients with a history of heart disease should not use it. Additionally, patients with impaired liver or kidney function, elderly patients, and patients with severe gastrointestinal ulcers should use this medication with caution. Patients who require electrolyte balance or sodium restriction should also be careful. When taking this medication, various adverse reactions may occur, including headaches, abdominal pain, diarrhea, skin rash, muscle pain, and liver function anomalies have been reported. In rare cases, severe allergic reactions or severe skin reactions may occur, so if symptoms are severe, consult a physician immediately. This drug can suppress gastric acid, leading to increased bacterial growth in the stomach, which may raise the risk of infections; thus, if diarrhea persists, consult healthcare professionals. Long-term use may increase fracture risk, so patients at risk for osteoporosis should undergo periodic checks. Also, magnesium levels may decrease, necessitating monitoring of serum magnesium levels during long-term use. This medication may interact with other drugs, so patients taking anticoagulants, antiviral agents, or anticonvulsants should inform their physician of their medication use. The safety of this medication during pregnancy has not been sufficiently established; thus, it should only be used when absolutely necessary. Breastfeeding women are advised not to use this medication. In case of overdose, there is no specific antidote, so appropriate treatment should be provided according to symptoms, and it should be kept out of reach of children.

Serious side effects

hives, severe swelling (edema), angioedema, anaphylaxis reaction/shock, severe rash with fever, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), difficulty breathing or shortness of breath, asthma attacks, liver failure, jaundice with or without

Mild side effects

• headache
• dizziness
• paresthesia
• drowsiness
• taste disturbance
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius to prolong the effectiveness of the medication.

Appearance

pale pink oblong film-coated tablets

Package unit

28 tablets/box [7 tablets/PTP x 4]