Atovanjett Tablets 10/40 mg

Adult dosage

This medication is administered once daily regardless of meals. The dosage range is 10/10mg to 10/80mg daily. An initial dose of 10/10mg or 10/20mg daily is recommended. For patients requiring a greater reduction in LDL cholesterol (more than 55%), an initial dose of 10/40mg daily is recommended. After initiating therapy or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks.

This medication can cause serious muscle problems; if symptoms such as acute muscle pain or muscle weakness occur, the doctor should be notified immediately. Patients with serious infections, hypotension, major surgery, trauma, severe metabolic abnormalities, etc., may need to temporarily suspend or discontinue this medication. People who are allergic to the active ingredients or excipients, have liver disease or persistently elevated liver enzymes, have muscle disorders, are pregnant or may become pregnant, are nursing mothers, or are taking certain antiviral medications should not take this medication. Additionally, patients with genetic issues such as lactose intolerance should not take this medication. Caution is advised in alcoholics or those with a history of liver disease, individuals with impaired kidney function, those with hypothyroidism, patients with a family history of muscle disorders or a history of taking muscle-toxic medications, seniors over 70 years of age, and those taking certain medications concomitantly. During the use of this medication, side effects such as muscle pain, joint pain, abdominal pain, liver dysfunction, etc., may occur, so they should consult their doctor if they appear. Regular liver function tests should be conducted, and if symptoms of liver damage occur, treatment should be stopped immediately. This medication is not to be used by women who are pregnant or breastfeeding, and appropriate contraception should be used by women of childbearing age. Safety and efficacy have not been established in children, so it is not recommended for them. Older adults are at higher risk for myopathy; therefore, caution is needed, but dosage adjustments are generally not necessary. This medication may interact with other drugs, so any concurrent medications should be reported to a doctor or pharmacist. There is no specific antidote for overdose, so treatment should be based on symptoms and liver function and muscular status should be monitored. This medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough + fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• elevation of liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White, biconvex, film-coated rectangular tablet

Package unit

30 tablets/box [10 tablets/PTP*3]