Ritovajet Tablets 10/40 Milligrams (Ezetimibe, Atorvastatin Calcium Hydrate)

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage range is from 10/10mg to 10/80mg daily. The recommended initial dose is either 10/10mg or 10/20mg once daily. For patients requiring a significant reduction in LDL-cholesterol, the recommended initial dose is 10/40mg once daily. After initiation, blood lipid levels should be monitored with intervals of more than 2 weeks, and dosages adjusted accordingly.

This medication can rarely cause muscle damage resulting in severe kidney problems; therefore, if severe muscle pain or weakness occurs, consult a physician immediately. Persons with allergies to this medication's active ingredients or components, those with liver issues or elevated liver enzyme levels, individuals with muscle disorders, pregnant women or women who may become pregnant, and nursing mothers should not take this medication. Individuals at higher risk for myopathy, such as those with alcohol dependence, poor liver function, kidney issues, or hypothyroidism, as well as the elderly, should be particularly cautious when taking this medication, and dosage adjustments or monitoring may be needed at the physician's discretion. This medication can impact liver function, so it is important to undergo liver function tests before and during administration, and to promptly inform a physician if symptoms of liver damage (e.g., jaundice, nausea, vomiting, fatigue) appear. During treatment with this medication, if muscle pain, weakness, fatigue, fever, or other symptoms develop, consult a physician immediately and receive muscle enzyme tests if necessary. This medication may interact with other drugs; therefore, be sure to inform your doctor or pharmacist if taking specific antibiotics, antivirals, immunosuppressants, fibrates, etc. Women of childbearing age should use proper contraceptive methods to avoid pregnancy while taking this medication, and if pregnancy is confirmed, they should stop taking it immediately and consult a physician. The safety and efficacy of this medication in children have not been established, and it is generally not recommended for them. Although older adults are at higher risk for myopathy and should exercise caution when taking, special dosage adjustments are usually not necessary. In the case of overdose, there is no specific antidote, so management should focus on symptomatic treatment and monitoring of liver function and muscle enzymes.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, yellowing of skin or eyes (jaundice), profound general malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius. Proper storage ensures the medication's effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle