Dutor Tablet 10/40 mg

Adult dosage

This medication is administered once daily without regard to meals. The dosage range is from 10/10 mg to 10/80 mg per day. An initial dose of 10/10 mg or 10/20 mg per day is recommended. For patients requiring greater reductions in LDL cholesterol, an initial dose of 10/40 mg per day is recommended. After starting treatment or adjusting the dose, check blood lipid levels at intervals of more than 2 weeks.

This medication can cause a rare side effect called rhabdomyolysis that may affect muscles, which increases the risk of kidney damage. Therefore, if severe muscle pain or weakness occurs, consult a doctor immediately. This drug should not be used in patients who are allergic to the active ingredient or excipients, or in those with liver disease or muscle disorders. Women who are pregnant or may become pregnant, as well as breastfeeding women, should not take this medication. Patients taking medications such as glecaprevir or pibrentasvir should also avoid this drug. Caution is advised for those with alcohol dependence, impaired liver function, weak kidney function, or hypothyroidism. Additionally, special attention is needed for elderly patients over 70 years old or those with a family history of muscle disorders. Patients taking fibrate medications alongside this drug may have an increased risk of muscle adverse reactions, so care should be taken. This drug can affect liver function, so it is essential to have liver function tests before and during treatment. If liver function worsens or jaundice symptoms appear, treatment should be stopped immediately. Blood sugar levels may rise during treatment, so diabetic patients should carefully manage their blood sugar. Caution is also required when driving or operating machinery due to possible dizziness. This drug can interact with various medications, so inform your doctor or pharmacist if you are taking other drugs. Women of childbearing age should use appropriate contraception while taking this medication, and it should be avoided if planning for pregnancy or during pregnancy. Safety for use in children has not been established and is not recommended. In case of overdose, there is no specific antidote, so symptomatic treatment and supportive therapy are required, and liver function and muscle status should be monitored.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Muscle pain
• abdominal pain
• increased liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• arthralgia
• muscle weakness
• back pain

This drug can be sensitive to air and moisture, so it should be stored in a tightly closed container. Avoid extremely hot or cold places, and it is best to keep it at room temperature between 1 degree to 30 degrees Celsius.

Appearance

White, oval, film-coated tablets that are convex on both sides

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)]