Atorvastatin/Ezetimibe Tablet 10/10 mg

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, the dose range is 10/10 mg to 10/80 mg per day, with a recommended starting dose of 10/10 mg or 10/20 mg per day. For patients requiring an LDL-cholesterol reduction of more than 55%, a starting dose of 10/40 mg per day is recommended. After initiating treatment or adjusting the dose, lipid levels should be checked at intervals of at least 2 weeks.

This medication may cause rare side effects affecting muscle tissue, which can result in severe muscle damage and kidney function issues; therefore, if severe muscle pain or weakness symptoms occur, consult a doctor immediately. This medication should not be used by those who are allergic to the active ingredients or components, individuals with severely impaired liver function, those with muscle disorders, pregnant or potentially pregnant women, nursing mothers, persons taking certain antiviral medications, and those with lactose intolerance. Patients who have a history of alcoholism or liver disease, those with severe liver function impairment, diminished kidney function, hypothyroid patients, those with a personal or family history of muscle disorders, elderly patients over 70, and individuals taking certain other medications should exercise caution while using this drug and seek medical attention if any abnormal symptoms occur. While taking this medication, symptoms like muscle pain, muscle weakness, abdominal pain, liver function abnormalities, etc., may appear; if these symptoms persist or worsen, inform your doctor. Regular tests for liver function and muscle-related tests are necessary, and if symptoms of liver function impairment or muscle issues arise, testing should be done immediately. This medication should not be given to women who are pregnant or nursing, and fertile women should use appropriate contraception while taking this drug. Not recommended in children as safety and efficacy have not been established, and caution is advised in the elderly due to the risk of myopathy. This drug can interact with several others, so if other medications are being taken, it is essential to inform a doctor or pharmacist, especially in combination with drugs that affect liver metabolism, as dose adjustment or monitoring may be necessary. Dizziness may occur while driving or operating machinery; thus, caution is needed. In case of overdose, there is no specific antidote, so treatment should focus on symptomatic management and supportive care, monitoring liver function and muscle condition. This medication should be stored out of reach of children and kept in its original packaging.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary incontinence

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• dizziness
• headache
• joint pain
• muscle weakness
• musculoskeletal pain
• bronchitis

This medication should be stored in a tightly closed container to prevent air and moisture from entering. The ideal temperature is between 1°C and 30°C at room temperature. Storing it this way will help maintain the drug's effectiveness over time.

Appearance

White, biconvex, rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]