Disambita Injection (Cholecalciferol)

Adult administration

Administer 200,000 IU of cholecalciferol by intramuscular injection. For the elderly, administer 100,000 IU of cholecalciferol by intramuscular injection. Ensure that the annual dose does not exceed 600,000 IU of cholecalciferol.

Child administration

Administer 200,000 IU of cholecalciferol by intramuscular injection.

This medication contains vitamin D, so it is essential to check the total vitamin D intake when taking fortified foods or other vitamin D products. Regularly monitor the calcium levels in the blood, and if the serum calcium level rises too much or if there is excessive calcium being excreted in urine, this medication should be discontinued. It is particularly important to continuously monitor blood and urine calcium levels for individuals with high calcium intake. When using this injectable medication, be cautious when opening the vial to avoid the risk of glass fragments mixing in. Patients with allergic reactions, hypercalcemia, kidney stones, kidney dysfunction, immobilization, certain illnesses, pregnant or breastfeeding women should not use this medication. While taking this medication, various side effects may appear, including headaches, fatigue, muscle pain, digestive disturbances, dehydration, high blood pressure, and kidney issues; consult a healthcare professional immediately if any unusual symptoms arise. For patients with low vitamin D levels, periodic blood tests should be performed to monitor their condition, and if renal function is impaired, adjust the dosage or discontinue use. Interactions may occur when taken with other medications, so individuals taking anticonvulsants, diuretics, antacids, or warfarin should inform their healthcare provider. In pregnancy, it is advisable not to use this medication due to the risk of harm to the fetus in case of overdose. Its safety and efficacy in children under 12 years of age have not been established; therefore, it is recommended not to use it in this age group. In case of overdose, discontinue this medication, reduce calcium intake, increase fluid intake, and consider treatment that promotes diuresis. Do not mix this medication with others, consume it quickly after opening, and dispose of any remaining medication.

Serious side effects

• Hypercalcemia
• hypercalciuria
• kidney dysfunction
• arrhythmias
• hypersensitivity
• rashes
• urticaria at the injection site

Mild side effects

Headaches, weakness, fatigue, muscle pain, loss of appetite, weight loss, growth retardation, nausea, vomiting, constipation, diarrhea, excessive thirst, frequent urination, dehydration, hypertension, calcium stones, tissue calcification in kidneys and blood vessels, excessive bone calcification, arrhythmias, mental symptoms, sensory disturbances, joint pain, muscle weakness, drowsiness, nitrogen retention, hypersensitivity, thirst, confusion, gas bloating, abdominal pain, metallic taste, dry mouth, rashes, itching, hypercalciuria, hypercalcemia,

This medication should be stored in a sealed container that blocks light, maintaining a temperature between 1 and 25 degrees Celsius. This helps preserve the medication's efficacy and prevents deterioration.

Appearance

A transparent solution of pale yellow color in brown glass ampoules.

Package unit

10 ampoules/box [1mL/ampoule]