Janurodi Tablets 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dosage of 100 mg for either monotherapy or combination therapy, with a maximum daily dosage of 100 mg. This medication can be taken without regard to meals. For patients with renal impairment, dosage adjustments are required based on kidney function. 1. For mild renal impairment (glomerular filtration rate of 60 to less than 90), dosage adjustments are not necessary. 2. For moderate renal impairment (glomerular filtration rate of 45 to less than 60), dosage adjustments are necessary.

This medication may cause severe allergic reactions after administration. If symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a doctor. This drug may cause serious inflammation of the pancreas, known as pancreatitis. Inform medical personnel immediately if symptoms such as abdominal pain, vomiting, or nausea appear. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients with hypersensitivity to the drug. Patients with impaired kidney function should have their dosage adjusted; those with kidney disease must consult a doctor. While taking this medication, hypoglycemic symptoms may occur, especially if taken with insulin or sulfonylurea, so blood glucose should be monitored closely, and the dosage of other medications should be adjusted if necessary. Severe joint pain or skin blistering may occur; contact medical personnel immediately if these symptoms arise. Use of this medication during pregnancy or breastfeeding is not recommended, and safety and efficacy have not been established in individuals under 18 years of age. In older adults, kidney function may be impaired, so kidney function tests are needed before and after administration. In cases of overdose, gastrointestinal removal of the drug and appropriate treatments like ECG monitoring may be necessary, and some may be removed by dialysis. This medication has low drug interaction potential, but caution is needed when used in combination with cyclosporine or digoxin; inform your doctor.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, severe allergic reactions, Stevens-Johnson syndrome, exfoliative dermatitis, severe skin reactions, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, acute renal failure, severe and debilitating joint pain, blistering dermatitis, difficulty breathing, pneumonia, diabetic complications, metabolic acidosis, cardiac arrest

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is advisable to maintain a storage temperature between 1 degrees and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Light orange, round, biconvex film-coated tablet

Package unit

30 tablets (10 tablets/PTP x 3)